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Synthesis of tetrafluorinated piperidines from nitrones via a visible-light-promoted annelation reaction
A method for the one-step construction of 3,3,4,4-tetrafluorinated piperidines from nitrones and readily accessible tetrafluorinated iodobromobutane is described. The reaction requires an excess amount of ascorbic acid as the terminal reductant and is performed in the presence of an iridium photocat...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783028/ https://www.ncbi.nlm.nih.gov/pubmed/33437323 http://dx.doi.org/10.3762/bjoc.16.260 |