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Are Nonsynonymous Transversions Generally More Deleterious than Nonsynonymous Transitions?
It has been suggested that, due to the structure of the genetic code, nonsynonymous transitions are less likely than transversions to cause radical changes in amino acid physicochemical properties so are on average less deleterious. This view was supported by some but not all mutagenesis experiments...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783172/ https://www.ncbi.nlm.nih.gov/pubmed/32805043 http://dx.doi.org/10.1093/molbev/msaa200 |