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ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei

DNA double-strand breaks (DSBs) are among the most deleterious lesions that threaten genome integrity. To address DSBs, eukaryotic cells of model organisms have evolved a complex network of cellular pathways that are able to detect DNA damage, activate a checkpoint response to delay cell cycle progr...

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Detalles Bibliográficos
Autores principales: Marin, Paula Andrea, Obonaga, Ricardo, Pavani, Raphael Souza, da Silva, Marcelo Santos, de Araujo, Christiane Bezerra, Lima, André Arruda, Avila, Carla Cristi, Cestari, Igor, Machado, Carlos Renato, Elias, Maria Carolina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783291/
https://www.ncbi.nlm.nih.gov/pubmed/33415107
http://dx.doi.org/10.3389/fcell.2020.602956