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ATR Kinase Is a Crucial Player Mediating the DNA Damage Response in Trypanosoma brucei
DNA double-strand breaks (DSBs) are among the most deleterious lesions that threaten genome integrity. To address DSBs, eukaryotic cells of model organisms have evolved a complex network of cellular pathways that are able to detect DNA damage, activate a checkpoint response to delay cell cycle progr...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783291/ https://www.ncbi.nlm.nih.gov/pubmed/33415107 http://dx.doi.org/10.3389/fcell.2020.602956 |