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Crosstalk between codon optimality and cis-regulatory elements dictates mRNA stability

BACKGROUND: The regulation of messenger RNA (mRNA) stability has a profound impact on gene expression dynamics during embryogenesis. For example, in animals, maternally deposited mRNAs are degraded after fertilization to enable new developmental trajectories. Regulatory sequences in 3′ untranslated...

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Detalles Bibliográficos
Autores principales:	Medina-Muñoz, Santiago Gerardo, Kushawah, Gopal, Castellano, Luciana Andrea, Diez, Michay, DeVore, Michelle Lynn, Salazar, María José Blanco, Bazzini, Ariel Alejandro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783504/ https://www.ncbi.nlm.nih.gov/pubmed/33402205 http://dx.doi.org/10.1186/s13059-020-02251-5

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