A novel TBX5 mutation predisposes to familial cardiac septal defects and atrial fibrillation as well as bicuspid aortic valve

TBX5 has been linked to Holt-Oram syndrome, with congenital heart defect (CHD) and atrial fibrillation (AF) being two major cardiac phenotypes. However, the prevalence of a TBX5 variation in patients with CHD and AF remains obscure. In this research, by sequencing analysis of TBX5 in 178 index patie...

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Detalles Bibliográficos
Autores principales: Jiang, Wei-Feng, Xu, Ying-Jia, Zhao, Cui-Mei, Wang, Xin-Hua, Qiu, Xing-Biao, Liu, Xu, Wu, Shao-Hui, Yang, Yi-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Human and Medical Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783509/
https://www.ncbi.nlm.nih.gov/pubmed/33306779
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783509/
https://www.ncbi.nlm.nih.gov/pubmed/33306779
http://dx.doi.org/10.1590/1678-4685-GMB-2020-0142

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