Estimation of C. elegans cell- and tissue volumes

Although C. elegans is one of the best-studied model organisms, an estimate of its cell sizes and tissues is missing. Here we used the Virtual Worm that is based on electron microscopy images to calculate a zeroth-order approximation of cell and tissue sizes of C. elegans. We conclude that the intes...

Descripción completa

Detalles Bibliográficos
Autores principales: Froehlich, Jonathan J, Rajewsky, Nikolaus, Ewald, Collin Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2021
Materias:
New Finding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783529/
https://www.ncbi.nlm.nih.gov/pubmed/33426507
http://dx.doi.org/10.17912/micropub.biology.000345
_version_ 1783632135528120320
author Froehlich, Jonathan J
Rajewsky, Nikolaus
Ewald, Collin Y
author_facet Froehlich, Jonathan J
Rajewsky, Nikolaus
Ewald, Collin Y
author_sort Froehlich, Jonathan J
collection PubMed
description Although C. elegans is one of the best-studied model organisms, an estimate of its cell sizes and tissues is missing. Here we used the Virtual Worm that is based on electron microscopy images to calculate a zeroth-order approximation of cell and tissue sizes of C. elegans. We conclude that the intestine is the largest tissue, followed by the hypodermis, gonads, body wall muscles, pharynx, and neurons. Thus, we provide an approximation of tissue volumes of young adult C. elegans.
format Online
Article
Text
id pubmed-7783529
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Caltech Library
record_format MEDLINE/PubMed
spelling pubmed-77835292021-01-07 Estimation of C. elegans cell- and tissue volumes Froehlich, Jonathan J Rajewsky, Nikolaus Ewald, Collin Y MicroPubl Biol New Finding Although C. elegans is one of the best-studied model organisms, an estimate of its cell sizes and tissues is missing. Here we used the Virtual Worm that is based on electron microscopy images to calculate a zeroth-order approximation of cell and tissue sizes of C. elegans. We conclude that the intestine is the largest tissue, followed by the hypodermis, gonads, body wall muscles, pharynx, and neurons. Thus, we provide an approximation of tissue volumes of young adult C. elegans. Caltech Library 2021-01-04 /pmc/articles/PMC7783529/ /pubmed/33426507 http://dx.doi.org/10.17912/micropub.biology.000345 Text en Copyright: © 2021 by the authors https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle New Finding
Froehlich, Jonathan J
Rajewsky, Nikolaus
Ewald, Collin Y
Estimation of C. elegans cell- and tissue volumes
title Estimation of C. elegans cell- and tissue volumes
title_full Estimation of C. elegans cell- and tissue volumes
title_fullStr Estimation of C. elegans cell- and tissue volumes
title_full_unstemmed Estimation of C. elegans cell- and tissue volumes
title_short Estimation of C. elegans cell- and tissue volumes
title_sort estimation of c. elegans cell- and tissue volumes
topic New Finding
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783529/
https://www.ncbi.nlm.nih.gov/pubmed/33426507
http://dx.doi.org/10.17912/micropub.biology.000345
work_keys_str_mv AT froehlichjonathanj estimationofceleganscellandtissuevolumes
AT rajewskynikolaus estimationofceleganscellandtissuevolumes
AT ewaldcolliny estimationofceleganscellandtissuevolumes

Ejemplares similares