Interleukin-1 Receptor Modulation Using β-Substituted α-Amino-γ-Lactam Peptides From Solid-Phase Synthesis and Diversification

As a key cytokine mediator of inflammation, interleukin-1β (IL-1β) binds to the IL-1 receptor (IL-1R) and activates various downstream signaling mediators, including NF-κB, which is required for immune vigilance and cellular protection. Toward the development of IL-1-targeting therapeutics which exh...

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Detalles Bibliográficos
Autores principales: Geranurimi, Azade, Cheng, Colin W. H., Quiniou, Christiane, Côté, France, Hou, Xin, Lahaie, Isabelle, Boudreault, Amarilys, Chemtob, Sylvain, Lubell, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783595/
https://www.ncbi.nlm.nih.gov/pubmed/33415098
http://dx.doi.org/10.3389/fchem.2020.610431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783595/
https://www.ncbi.nlm.nih.gov/pubmed/33415098
http://dx.doi.org/10.3389/fchem.2020.610431

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