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Influence of a genetic variant of CHAT gene over the profile of plasma soluble ChAT in Alzheimer disease
The choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) are fundamental to neurophysiological functions of the central cholinergic system. We confirmed and quantified the presence of extracellular ChAT protein in human plasma and also characterized ChAT and VAChT polymor...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Genética
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783728/ https://www.ncbi.nlm.nih.gov/pubmed/33306773 http://dx.doi.org/10.1590/1678-4685-GMB-2019-0404 |