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Influence of a genetic variant of CHAT gene over the profile of plasma soluble ChAT in Alzheimer disease

The choline acetyltransferase (ChAT) and vesicular acetylcholine transporter (VAChT) are fundamental to neurophysiological functions of the central cholinergic system. We confirmed and quantified the presence of extracellular ChAT protein in human plasma and also characterized ChAT and VAChT polymor...

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Detalles Bibliográficos
Autores principales: Rocha-Dias, Patricia Fernanda, Simao-Silva, Daiane Priscila, da Silva, Saritha Suellen Lopes, Piovezan, Mauro Roberto, Souza, Ricardo Krause M., Darreh-Shori, Taher., Furtado-Alle, Lupe, Souza, Ricardo Lehtonen Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783728/
https://www.ncbi.nlm.nih.gov/pubmed/33306773
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0404