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In silico investigation on alkaloids of Rauwolfia serpentina as potential inhibitors of 3-hydroxy-3-methyl-glutaryl-CoA reductase

Present work aimed to investigate the in silico activity of the alkaloids of roots of Rauwolfia serpentina as inhibitors of 3-hydroxy-3-methyl-glutaryl-CoA reductase (HMGCR). For this purpose, the three-dimensional (3D) structure of the protein HMGCR (PDB ID: 1HW9) was downloaded from Protein Data B...

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Detalles Bibliográficos
Autores principales:	Azmi, Muhammad Bilal, Sultana, Saleha, Naeem, Sadaf, Qureshi, Shamim Akhtar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783793/ https://www.ncbi.nlm.nih.gov/pubmed/33424361 http://dx.doi.org/10.1016/j.sjbs.2020.10.066

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