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Decoding variants in drug-metabolizing enzymes and transporters in solid tumor patients by whole-exome sequencing

BACKGROUND: Pharmacogenetics is involved in customizing therapy according to the genetic makeup of an individual, and is applicable for chemotherapy, radiotherapy as well as targeted therapy. Drug metabolizing enzymes (DMEs) involving both phase I, and phase II reactions are widely studied. Our stud...

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Detalles Bibliográficos
Autores principales:	Aboul-Soud, Mourad A.M., Alzahrani, Alhussain J., Mahmoud, Amer
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783809/ https://www.ncbi.nlm.nih.gov/pubmed/33424349 http://dx.doi.org/10.1016/j.sjbs.2020.10.052

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