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A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)

The aim of the present study was to investigate the comparative effects of pesticides Chlorfenapyr, Dimethoate and Acetamiprid on the health of Cirrhinus mrigala under long term exposure. Eighty C. mrigala were divided in four equal groups; one control and three treated groups. The blood was collect...

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Autores principales: Ghayyur, Shehzad, Khan, Muhammad Fiaz, Tabassum, Sadia, Ahmad, Munawar Saleem, Sajid, Muhammad, Badshah, Khandil, Khan, Muhammad Azhar, Saira, Ghayyur, Shahryar, Khan, Naveed Ahmad, Ahmad, Bilal, Qamer, Samina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783810/
https://www.ncbi.nlm.nih.gov/pubmed/33424346
http://dx.doi.org/10.1016/j.sjbs.2020.10.049
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author Ghayyur, Shehzad
Khan, Muhammad Fiaz
Tabassum, Sadia
Ahmad, Munawar Saleem
Sajid, Muhammad
Badshah, Khandil
Khan, Muhammad Azhar
Saira
Ghayyur, Shahryar
Khan, Naveed Ahmad
Ahmad, Bilal
Qamer, Samina
author_facet Ghayyur, Shehzad
Khan, Muhammad Fiaz
Tabassum, Sadia
Ahmad, Munawar Saleem
Sajid, Muhammad
Badshah, Khandil
Khan, Muhammad Azhar
Saira
Ghayyur, Shahryar
Khan, Naveed Ahmad
Ahmad, Bilal
Qamer, Samina
author_sort Ghayyur, Shehzad
collection PubMed
description The aim of the present study was to investigate the comparative effects of pesticides Chlorfenapyr, Dimethoate and Acetamiprid on the health of Cirrhinus mrigala under long term exposure. Eighty C. mrigala were divided in four equal groups; one control and three treated groups. The blood was collected from both control and treated groups at intervals of 10th, 20th and 30th days for hemato-biochemistry and histopathological alterations. The result indicates significant difference (P < 0.05) in RBCs, Hb, PCV and MCHC whereas elevation in WBCs and Platelets counts were recorded. In 10th day sampling, MCV value of Dimethoate and Acetamiprid treatment had no difference in comparison with the control group, however it is significantly increased (P < 0.05) in rest of sampling. The MCH value of exposed fish showed significant increased (P < 0.05) after 20th and 30th days for Chlorfenapyr and after 30th days for Acetamiprid exposure while insignificantly increased for rest of sampling. It was also found that these pesticides significantly decrease (p < 0.05) the T3 and T4 levels while increase in the TSH, cortical, ALP, AST, ALT and LDH levels in the serum of the treated fishes in contrast to control group. Similarly, histopathological analysis of gills and liver showed significant alterations in all the treated groups. Toxicity trends of these pesticides was ranked as Chlorfenapyr > Acetamiprid > Dimethoate. It is concluded that indiscriminate use of such pesticides poses a noxious threat to non-target organisms, harm the ecosystems and jeopardizes human health.
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spelling pubmed-77838102021-01-08 A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822) Ghayyur, Shehzad Khan, Muhammad Fiaz Tabassum, Sadia Ahmad, Munawar Saleem Sajid, Muhammad Badshah, Khandil Khan, Muhammad Azhar Saira Ghayyur, Shahryar Khan, Naveed Ahmad Ahmad, Bilal Qamer, Samina Saudi J Biol Sci Original Article The aim of the present study was to investigate the comparative effects of pesticides Chlorfenapyr, Dimethoate and Acetamiprid on the health of Cirrhinus mrigala under long term exposure. Eighty C. mrigala were divided in four equal groups; one control and three treated groups. The blood was collected from both control and treated groups at intervals of 10th, 20th and 30th days for hemato-biochemistry and histopathological alterations. The result indicates significant difference (P < 0.05) in RBCs, Hb, PCV and MCHC whereas elevation in WBCs and Platelets counts were recorded. In 10th day sampling, MCV value of Dimethoate and Acetamiprid treatment had no difference in comparison with the control group, however it is significantly increased (P < 0.05) in rest of sampling. The MCH value of exposed fish showed significant increased (P < 0.05) after 20th and 30th days for Chlorfenapyr and after 30th days for Acetamiprid exposure while insignificantly increased for rest of sampling. It was also found that these pesticides significantly decrease (p < 0.05) the T3 and T4 levels while increase in the TSH, cortical, ALP, AST, ALT and LDH levels in the serum of the treated fishes in contrast to control group. Similarly, histopathological analysis of gills and liver showed significant alterations in all the treated groups. Toxicity trends of these pesticides was ranked as Chlorfenapyr > Acetamiprid > Dimethoate. It is concluded that indiscriminate use of such pesticides poses a noxious threat to non-target organisms, harm the ecosystems and jeopardizes human health. Elsevier 2021-01 2020-11-02 /pmc/articles/PMC7783810/ /pubmed/33424346 http://dx.doi.org/10.1016/j.sjbs.2020.10.049 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Ghayyur, Shehzad
Khan, Muhammad Fiaz
Tabassum, Sadia
Ahmad, Munawar Saleem
Sajid, Muhammad
Badshah, Khandil
Khan, Muhammad Azhar
Saira
Ghayyur, Shahryar
Khan, Naveed Ahmad
Ahmad, Bilal
Qamer, Samina
A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title_full A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title_fullStr A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title_full_unstemmed A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title_short A comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish Cirrhinus mrigala (Hamilton, 1822)
title_sort comparative study on the effects of selected pesticides on hemato-biochemistry and tissue histology of freshwater fish cirrhinus mrigala (hamilton, 1822)
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783810/
https://www.ncbi.nlm.nih.gov/pubmed/33424346
http://dx.doi.org/10.1016/j.sjbs.2020.10.049
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