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Systemically administered neurotensin receptor agonist produces antinociception through activation of spinally projecting serotonergic neurons in the rostral ventromedial medulla

BACKGROUND: Supraspinal delivery of neurotensin (NTS), which may contribute to the effect of a systemically administered agonist, has been reported to be either pronociceptive or antinociceptive. Here, we evaluated the effects of systemically administered NTSR1 agonist in a rat model of neuropathic...

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Detalles Bibliográficos
Autores principales: Li, Yaqun, Kang, Dong Ho, Kim, Woong Mo, Lee, Hyung Gon, Kim, Seung Hoon, You, Hyun Eung, Choi, Jeong Il, Yoon, Myung Ha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783846/
https://www.ncbi.nlm.nih.gov/pubmed/33380568
http://dx.doi.org/10.3344/kjp.2021.34.1.58