Toll-like receptor 4/nuclear factor-kappa B pathway is involved in radicular pain by encouraging spinal microglia activation and inflammatory response in a rat model of lumbar disc herniation

BACKGROUND: Lumbar disc herniation (LDH) is a common cause of radicular pain, but the mechanism is not clear. In this study, we investigated the engagement of toll-like receptor 4 (TLR4) and the nuclear factor-kappa B (NF-κB) in radicular pain and its possible mechanisms. METHODS: An LDH model was i...

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Detalles Bibliográficos
Autores principales: Zhu, Lirong, Huang, Yangliang, Hu, Yuming, Tang, Qian, Zhong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2021
Materias:
Experimental Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7783850/
https://www.ncbi.nlm.nih.gov/pubmed/33380567
http://dx.doi.org/10.3344/kjp.2021.34.1.47

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