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Conditional knock out of transcription factor CTCF in excitatory neurons induces cognitive deficiency
CCCTC-binding factor (CTCF) is a transcription factor that is involved in organizing chromatin structure. A reduction of CTCF expression is known to develop distinct clinical features. Furthermore, conditional knock out (cKO) study revealed reactive gliosis of astrocytes and microglia followed by ag...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784033/ https://www.ncbi.nlm.nih.gov/pubmed/33402211 http://dx.doi.org/10.1186/s13041-020-00716-z |