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Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia

INTRODUCTION: Limited information exists on health care workers’ (HCWs) perceptions about use of multidose vaccine vials and their preferences about doses per container (DPC). We present findings from qualitative studies conducted in Senegal, Vietnam, and Zambia to explore HCWs’ behavior regarding o...

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Autores principales: Kanagat, Natasha, Krudwig, Kirstin, Wilkins, Karen A., Kaweme, Sydney, Phiri, Guissimon, Mwansa, Frances D., Mvundura, Mercy, Robertson, Joanie, Kristensen, Debra, Gueye, Abdoulaye, Dao, Sang D., Thai, Pham Q., Nguyen, Huyen T., Tran, Thang C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Global Health: Science and Practice 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784065/
https://www.ncbi.nlm.nih.gov/pubmed/33361235
http://dx.doi.org/10.9745/GHSP-D-20-00112
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author Kanagat, Natasha
Krudwig, Kirstin
Wilkins, Karen A.
Kaweme, Sydney
Phiri, Guissimon
Mwansa, Frances D.
Mvundura, Mercy
Robertson, Joanie
Kristensen, Debra
Gueye, Abdoulaye
Dao, Sang D.
Thai, Pham Q.
Nguyen, Huyen T.
Tran, Thang C.
author_facet Kanagat, Natasha
Krudwig, Kirstin
Wilkins, Karen A.
Kaweme, Sydney
Phiri, Guissimon
Mwansa, Frances D.
Mvundura, Mercy
Robertson, Joanie
Kristensen, Debra
Gueye, Abdoulaye
Dao, Sang D.
Thai, Pham Q.
Nguyen, Huyen T.
Tran, Thang C.
author_sort Kanagat, Natasha
collection PubMed
description INTRODUCTION: Limited information exists on health care workers’ (HCWs) perceptions about use of multidose vaccine vials and their preferences about doses per container (DPC). We present findings from qualitative studies conducted in Senegal, Vietnam, and Zambia to explore HCWs’ behavior regarding opening vials and their perceptions and preferences for the number of doses in vials of BCG and measles-containing vaccine (MCV). Zambia and Senegal currently offer MCV in 10-dose vials and BCG in 20-dose vials; 10-dose vials are used for both vaccines in Vietnam. Unused doses in vials of these reconstituted vaccines must be discarded within 6 hours. METHODS: Key informant interviews (KIIs) were conducted with frontline HCWs in Senegal, Vietnam, and Zambia. In Senegal and Vietnam, the KIIs were conducted as part of broader formative research; in Zambia, KIIs were conducted in control districts using 10-dose MCV vials only and in intervention districts that switched from 10- to 5-dose vials during the study. During analysis, themes common to all 3 countries were synthesized. Critical themes relevant to country contexts were also examined. RESULTS: HCWs in all 3 countries preferred containers with fewer doses for BCG and MCV to reduce wastage and increase the likelihood of vaccinating every eligible child. HCWs in Senegal and HCWs using 10-dose vials in Zambia reported sending unvaccinated children away because not enough children were present to warrant opening a new vial. In Vietnam, where sessions are typically held monthly, and in Zambia when the 5-dose vials were used, almost all HCWs reported opening a vial of MCV for even 1 child. DISCUSSION: HCWs prefer vials with fewer DPC. Their concerns about balancing coverage and wastage influence their decisions to vaccinate every eligible child; and their perspectives are crucial to ensuring that all target populations are reached with vaccines in a timely manner.
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spelling pubmed-77840652021-02-24 Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia Kanagat, Natasha Krudwig, Kirstin Wilkins, Karen A. Kaweme, Sydney Phiri, Guissimon Mwansa, Frances D. Mvundura, Mercy Robertson, Joanie Kristensen, Debra Gueye, Abdoulaye Dao, Sang D. Thai, Pham Q. Nguyen, Huyen T. Tran, Thang C. Glob Health Sci Pract Original Article INTRODUCTION: Limited information exists on health care workers’ (HCWs) perceptions about use of multidose vaccine vials and their preferences about doses per container (DPC). We present findings from qualitative studies conducted in Senegal, Vietnam, and Zambia to explore HCWs’ behavior regarding opening vials and their perceptions and preferences for the number of doses in vials of BCG and measles-containing vaccine (MCV). Zambia and Senegal currently offer MCV in 10-dose vials and BCG in 20-dose vials; 10-dose vials are used for both vaccines in Vietnam. Unused doses in vials of these reconstituted vaccines must be discarded within 6 hours. METHODS: Key informant interviews (KIIs) were conducted with frontline HCWs in Senegal, Vietnam, and Zambia. In Senegal and Vietnam, the KIIs were conducted as part of broader formative research; in Zambia, KIIs were conducted in control districts using 10-dose MCV vials only and in intervention districts that switched from 10- to 5-dose vials during the study. During analysis, themes common to all 3 countries were synthesized. Critical themes relevant to country contexts were also examined. RESULTS: HCWs in all 3 countries preferred containers with fewer doses for BCG and MCV to reduce wastage and increase the likelihood of vaccinating every eligible child. HCWs in Senegal and HCWs using 10-dose vials in Zambia reported sending unvaccinated children away because not enough children were present to warrant opening a new vial. In Vietnam, where sessions are typically held monthly, and in Zambia when the 5-dose vials were used, almost all HCWs reported opening a vial of MCV for even 1 child. DISCUSSION: HCWs prefer vials with fewer DPC. Their concerns about balancing coverage and wastage influence their decisions to vaccinate every eligible child; and their perspectives are crucial to ensuring that all target populations are reached with vaccines in a timely manner. Global Health: Science and Practice 2020-12-23 /pmc/articles/PMC7784065/ /pubmed/33361235 http://dx.doi.org/10.9745/GHSP-D-20-00112 Text en © Kanagat et al. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly cited. To view a copy of the license, visit http://creativecommons.org/licenses/by/4.0/. When linking to this article, please use the following permanent link: https://doi.org/10.9745/GHSP-D-20-00112
spellingShingle Original Article
Kanagat, Natasha
Krudwig, Kirstin
Wilkins, Karen A.
Kaweme, Sydney
Phiri, Guissimon
Mwansa, Frances D.
Mvundura, Mercy
Robertson, Joanie
Kristensen, Debra
Gueye, Abdoulaye
Dao, Sang D.
Thai, Pham Q.
Nguyen, Huyen T.
Tran, Thang C.
Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title_full Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title_fullStr Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title_full_unstemmed Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title_short Health Care Worker Preferences and Perspectives on Doses per Container for 2 Lyophilized Vaccines in Senegal, Vietnam, and Zambia
title_sort health care worker preferences and perspectives on doses per container for 2 lyophilized vaccines in senegal, vietnam, and zambia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784065/
https://www.ncbi.nlm.nih.gov/pubmed/33361235
http://dx.doi.org/10.9745/GHSP-D-20-00112
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