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Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients

BACKGROUND: The aim of this study was to compare the efficacy and safety of oncoplastic breast-conserving therapy (OBCT) and SBCT (standard breast-conserving therapy) in breast cancer surgery. MATERIAL/METHODS: We enrolled 192 breast cancer patients who underwent breast-conserving surgery during Jan...

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Autores principales: Zhou, Yuan, Liu, Yixiao, Wang, Yu, Wu, Yanfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784144/
https://www.ncbi.nlm.nih.gov/pubmed/33384404
http://dx.doi.org/10.12659/MSM.927015
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author Zhou, Yuan
Liu, Yixiao
Wang, Yu
Wu, Yanfei
author_facet Zhou, Yuan
Liu, Yixiao
Wang, Yu
Wu, Yanfei
author_sort Zhou, Yuan
collection PubMed
description BACKGROUND: The aim of this study was to compare the efficacy and safety of oncoplastic breast-conserving therapy (OBCT) and SBCT (standard breast-conserving therapy) in breast cancer surgery. MATERIAL/METHODS: We enrolled 192 breast cancer patients who underwent breast-conserving surgery during January 2015 to April 2018. The surgery strategies of OBCT and SBCT were performed according to the patients’ condition. For measurement of surgical cosmetic effects, the Harris scale, the modified objective scores, and the subjective evaluation were all used. The basic clinical characteristics, intraoperative indices, postoperative complications, metastasis, and recurrence during the 2-year follow-up were recorded. RESULTS: The mean surgical time was remarkably longer and the resected volume was markedly larger in the OBCT group than in the SBCT group. The excellent and good ratios of Harris scale, the modified objective scores, and the ratio of very satisfied and satisfied patients by subjective scale were all significantly higher in the OBCT group than in the SBCT group. The occurrence rates of seroma and poor incision healing were remarkably lower in the OBCT group. No significant difference was found for metastasis and recurrence. CONCLUSIONS: OBCT had better cosmetic effects, fewer complications, and no adverse effects on metastasis and recurrence.
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spelling pubmed-77841442021-01-07 Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients Zhou, Yuan Liu, Yixiao Wang, Yu Wu, Yanfei Med Sci Monit Clinical Research BACKGROUND: The aim of this study was to compare the efficacy and safety of oncoplastic breast-conserving therapy (OBCT) and SBCT (standard breast-conserving therapy) in breast cancer surgery. MATERIAL/METHODS: We enrolled 192 breast cancer patients who underwent breast-conserving surgery during January 2015 to April 2018. The surgery strategies of OBCT and SBCT were performed according to the patients’ condition. For measurement of surgical cosmetic effects, the Harris scale, the modified objective scores, and the subjective evaluation were all used. The basic clinical characteristics, intraoperative indices, postoperative complications, metastasis, and recurrence during the 2-year follow-up were recorded. RESULTS: The mean surgical time was remarkably longer and the resected volume was markedly larger in the OBCT group than in the SBCT group. The excellent and good ratios of Harris scale, the modified objective scores, and the ratio of very satisfied and satisfied patients by subjective scale were all significantly higher in the OBCT group than in the SBCT group. The occurrence rates of seroma and poor incision healing were remarkably lower in the OBCT group. No significant difference was found for metastasis and recurrence. CONCLUSIONS: OBCT had better cosmetic effects, fewer complications, and no adverse effects on metastasis and recurrence. International Scientific Literature, Inc. 2020-01-01 /pmc/articles/PMC7784144/ /pubmed/33384404 http://dx.doi.org/10.12659/MSM.927015 Text en © Med Sci Monit, 2021 This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) )
spellingShingle Clinical Research
Zhou, Yuan
Liu, Yixiao
Wang, Yu
Wu, Yanfei
Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title_full Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title_fullStr Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title_full_unstemmed Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title_short Comparison of Oncoplastic Breast-Conserving Therapy and Standard Breast-Conserving Therapy in Early-Stage Breast Cancer Patients
title_sort comparison of oncoplastic breast-conserving therapy and standard breast-conserving therapy in early-stage breast cancer patients
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784144/
https://www.ncbi.nlm.nih.gov/pubmed/33384404
http://dx.doi.org/10.12659/MSM.927015
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