The association of APOE ε4 with cognitive function over the adult life course and incidence of dementia: 20 years follow-up of the Whitehall II study

BACKGROUND: Approximately 25% of the general population carries at least one ε4 allele of the Apolipoprotein E (APOE ε4), the strongest genetic risk factor for late onset Alzheimer’s disease. Beyond its association with late-onset dementia, the association between APOE ε4 and change in cognition ove...

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Detalles Bibliográficos
Autores principales: Gharbi-Meliani, Amin, Dugravot, Aline, Sabia, Séverine, Regy, Melina, Fayosse, Aurore, Schnitzler, Alexis, Kivimäki, Mika, Singh-Manoux, Archana, Dumurgier, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784268/
https://www.ncbi.nlm.nih.gov/pubmed/33397450
http://dx.doi.org/10.1186/s13195-020-00740-0

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