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Siglec-E retards atherosclerosis by inhibiting CD36-mediated foam cell formation

BACKGROUND: The accumulation of lipid-laden macrophages, foam cells, within sub-endothelial intima is a key feature of early atherosclerosis. Siglec-E, a mouse orthologue of human Siglec-9, is a sialic acid binding lectin predominantly expressed on the surface of myeloid cells to transduce inhibitor...

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Detalles Bibliográficos
Autores principales:	Hsu, Yaw-Wen, Hsu, Fu-Fei, Chiang, Ming-Tsai, Tsai, Dong-Lin, Li, Fu-An, Angata, Takashi, Crocker, Paul R., Chau, Lee-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784283/ https://www.ncbi.nlm.nih.gov/pubmed/33397354 http://dx.doi.org/10.1186/s12929-020-00698-z

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