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Disome-seq reveals widespread ribosome collisions that promote cotranslational protein folding
BACKGROUND: The folding of proteins is challenging in the highly crowded and sticky environment of a cell. Regulation of translation elongation may play a crucial role in ensuring the correct folding of proteins. Much of our knowledge regarding translation elongation comes from the sequencing of mRN...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784341/ https://www.ncbi.nlm.nih.gov/pubmed/33402206 http://dx.doi.org/10.1186/s13059-020-02256-0 |