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Will the extraction of COVID-19 from wastewater help flatten the curve?

With the potentially fatal effect of COVID-19 and its devastating impact on economies worldwide, some environmental scientist has suggested the use of waste from household sewage to trace the movement of SARS-CoV-2, within a given country. However, this approach is not without challenges where devel...

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Autores principales: Atangana, Ernestine, Oberholster, Paul J., Turton, Anthony R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784541/
https://www.ncbi.nlm.nih.gov/pubmed/33445015
http://dx.doi.org/10.1016/j.chemosphere.2020.129429
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author Atangana, Ernestine
Oberholster, Paul J.
Turton, Anthony R.
author_facet Atangana, Ernestine
Oberholster, Paul J.
Turton, Anthony R.
author_sort Atangana, Ernestine
collection PubMed
description With the potentially fatal effect of COVID-19 and its devastating impact on economies worldwide, some environmental scientist has suggested the use of waste from household sewage to trace the movement of SARS-CoV-2, within a given country. However, this approach is not without challenges where developing countries lack proper and adequate hygiene and sanitation, resulting in widespread defecation. Limited scientific research has been done to determine how many times a recently infected person can defecate and the quantification of SARS-CoV-2 found in a single expel. On the other hand, there is no detailed research to specify where the heavy viral load of SARS-CoV-2 can be found in human excreta. In this paper, we present some obstacles that this approach could face in the absence of an intense lockdown in developing nations such as sub-Saharan countries. To achieve this, we identify some research needs that will strengthen our understanding of the transmission, occurrence, and persistence of SARS-CoV-2 in sewage and wastewater, including the life-span that depends on temperature. A methodology to follow in the process of identifying a hotspot on a small scale using some mathematical distributions, including the normal distribution, log-normal distribution, and the most complex one known as Blancmange function, was presented with some examples. Our investigation showed that this method might have some challenges, especially in developing countries (sub-Sahara countries) where open latrine usage is very high. Some recommendations we suggested to ensure the efficiency of such a method on a small scale. However, in general, it is essential to note the extraction/detection method will not help more than the testing method used all over the world to trace SARS-CoV-2 -19 in humans.
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spelling pubmed-77845412021-01-06 Will the extraction of COVID-19 from wastewater help flatten the curve? Atangana, Ernestine Oberholster, Paul J. Turton, Anthony R. Chemosphere Article With the potentially fatal effect of COVID-19 and its devastating impact on economies worldwide, some environmental scientist has suggested the use of waste from household sewage to trace the movement of SARS-CoV-2, within a given country. However, this approach is not without challenges where developing countries lack proper and adequate hygiene and sanitation, resulting in widespread defecation. Limited scientific research has been done to determine how many times a recently infected person can defecate and the quantification of SARS-CoV-2 found in a single expel. On the other hand, there is no detailed research to specify where the heavy viral load of SARS-CoV-2 can be found in human excreta. In this paper, we present some obstacles that this approach could face in the absence of an intense lockdown in developing nations such as sub-Saharan countries. To achieve this, we identify some research needs that will strengthen our understanding of the transmission, occurrence, and persistence of SARS-CoV-2 in sewage and wastewater, including the life-span that depends on temperature. A methodology to follow in the process of identifying a hotspot on a small scale using some mathematical distributions, including the normal distribution, log-normal distribution, and the most complex one known as Blancmange function, was presented with some examples. Our investigation showed that this method might have some challenges, especially in developing countries (sub-Sahara countries) where open latrine usage is very high. Some recommendations we suggested to ensure the efficiency of such a method on a small scale. However, in general, it is essential to note the extraction/detection method will not help more than the testing method used all over the world to trace SARS-CoV-2 -19 in humans. Elsevier Ltd. 2021-05 2021-01-05 /pmc/articles/PMC7784541/ /pubmed/33445015 http://dx.doi.org/10.1016/j.chemosphere.2020.129429 Text en © 2020 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Atangana, Ernestine
Oberholster, Paul J.
Turton, Anthony R.
Will the extraction of COVID-19 from wastewater help flatten the curve?
title Will the extraction of COVID-19 from wastewater help flatten the curve?
title_full Will the extraction of COVID-19 from wastewater help flatten the curve?
title_fullStr Will the extraction of COVID-19 from wastewater help flatten the curve?
title_full_unstemmed Will the extraction of COVID-19 from wastewater help flatten the curve?
title_short Will the extraction of COVID-19 from wastewater help flatten the curve?
title_sort will the extraction of covid-19 from wastewater help flatten the curve?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784541/
https://www.ncbi.nlm.nih.gov/pubmed/33445015
http://dx.doi.org/10.1016/j.chemosphere.2020.129429
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