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AAV3-miRNA vectors for growth suppression of human hepatocellular carcinoma cells in vitro and human liver tumors in a murine xenograft model in vivo

We have previously reported that recombinant adeno-associated virus serotype 3 (AAV3) vectors transduce human liver tumors more efficiently in a mouse xenograft model following systemic administration. Others have utilized AAV8 vectors expressing miR-26a and miR-122 to achieve near total inhibition...

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Detalles Bibliográficos
Autores principales:	Yin, Ling, Keeler, Geoffrey D., Zhang, Yuanhui, Hoffman, Brad E., Ling, Chen, Qing, Keyun, Srivastava, Arun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784898/ https://www.ncbi.nlm.nih.gov/pubmed/32152434 http://dx.doi.org/10.1038/s41434-020-0140-1

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