Cargando…

Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827

Cocos nucifera Linn., which contain lauric acid has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the C. nucifera L. Extract from Kopyor coconut. Extract were tested for...

Descripción completa

Detalles Bibliográficos
Autores principales: Hariyadi, Dewi Melani, Isnaeni, Isnaeni, Sudarma, Sisunandar, Suciati, Suciati, Rosita, Noorma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784937/
https://www.ncbi.nlm.nih.gov/pubmed/33425708
http://dx.doi.org/10.4103/japtr.JAPTR_51_20
_version_ 1783632370323161088
author Hariyadi, Dewi Melani
Isnaeni, Isnaeni
Sudarma, Sisunandar
Suciati, Suciati
Rosita, Noorma
author_facet Hariyadi, Dewi Melani
Isnaeni, Isnaeni
Sudarma, Sisunandar
Suciati, Suciati
Rosita, Noorma
author_sort Hariyadi, Dewi Melani
collection PubMed
description Cocos nucifera Linn., which contain lauric acid has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the C. nucifera L. Extract from Kopyor coconut. Extract were tested for antibacterial against P. acnes ATCC 11827. In this research, C. nucifera L. extract of 1 and 5% were formulated as an active agent of peel off antiacne emulgel mask-containing carbomer 940 in various concentration (1% and 1.5%). The peel-off emulgel mask of C. nucifera L extract was then evaluated in terms of viscosity, pH, drying time, spreadability, and antibacterial activity. The selected formula was formula containing 5% of extract and 1% of carbomer 940. This formula had pH that suitable with skin pH 4.5–6.5, had good spreadability, and also produced highest antibacterial activity against P. acnes.
format Online
Article
Text
id pubmed-7784937
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-77849372021-01-07 Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827 Hariyadi, Dewi Melani Isnaeni, Isnaeni Sudarma, Sisunandar Suciati, Suciati Rosita, Noorma J Adv Pharm Technol Res Original Article Cocos nucifera Linn., which contain lauric acid has been known had antibacterial activity against Propionibacterium acnes that usually improve severe of pimple. Current study investigated optimum formula of emulgel mask based on the C. nucifera L. Extract from Kopyor coconut. Extract were tested for antibacterial against P. acnes ATCC 11827. In this research, C. nucifera L. extract of 1 and 5% were formulated as an active agent of peel off antiacne emulgel mask-containing carbomer 940 in various concentration (1% and 1.5%). The peel-off emulgel mask of C. nucifera L extract was then evaluated in terms of viscosity, pH, drying time, spreadability, and antibacterial activity. The selected formula was formula containing 5% of extract and 1% of carbomer 940. This formula had pH that suitable with skin pH 4.5–6.5, had good spreadability, and also produced highest antibacterial activity against P. acnes. Wolters Kluwer - Medknow 2020 2020-10-10 /pmc/articles/PMC7784937/ /pubmed/33425708 http://dx.doi.org/10.4103/japtr.JAPTR_51_20 Text en Copyright: © 2020 Journal of Advanced Pharmaceutical Technology & Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Hariyadi, Dewi Melani
Isnaeni, Isnaeni
Sudarma, Sisunandar
Suciati, Suciati
Rosita, Noorma
Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title_full Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title_fullStr Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title_full_unstemmed Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title_short Peel-off emulgel mask of Cocos nucifera L. Extract using gelling agent carbomer 940 as antiacne against Propionibacterium acnes ATCC 11827
title_sort peel-off emulgel mask of cocos nucifera l. extract using gelling agent carbomer 940 as antiacne against propionibacterium acnes atcc 11827
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784937/
https://www.ncbi.nlm.nih.gov/pubmed/33425708
http://dx.doi.org/10.4103/japtr.JAPTR_51_20
work_keys_str_mv AT hariyadidewimelani peeloffemulgelmaskofcocosnuciferalextractusinggellingagentcarbomer940asantiacneagainstpropionibacteriumacnesatcc11827
AT isnaeniisnaeni peeloffemulgelmaskofcocosnuciferalextractusinggellingagentcarbomer940asantiacneagainstpropionibacteriumacnesatcc11827
AT sudarmasisunandar peeloffemulgelmaskofcocosnuciferalextractusinggellingagentcarbomer940asantiacneagainstpropionibacteriumacnesatcc11827
AT suciatisuciati peeloffemulgelmaskofcocosnuciferalextractusinggellingagentcarbomer940asantiacneagainstpropionibacteriumacnesatcc11827
AT rositanoorma peeloffemulgelmaskofcocosnuciferalextractusinggellingagentcarbomer940asantiacneagainstpropionibacteriumacnesatcc11827