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Effect of corneal stromal pocket irrigation in small-incision lenticule extraction
OBJECTIVES: To investigate the effect of corneal stromal pocket irrigation after small-incision lenticule extraction (SMILE) on visual acuity, intraocular pressure (IOP), corneal parameters and complications after surgery. METHODS: A total of 242 eyes of 121 patients undergoing SMILE were enrolled i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784961/ https://www.ncbi.nlm.nih.gov/pubmed/32157182 http://dx.doi.org/10.1038/s41433-020-0840-1 |
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author | Wang, Han Ding, Hui Ouyang, Bo-wen Yang, Zhenduo Zhong, Tan Fan, Hongming Zhong, Xingwu |
author_facet | Wang, Han Ding, Hui Ouyang, Bo-wen Yang, Zhenduo Zhong, Tan Fan, Hongming Zhong, Xingwu |
author_sort | Wang, Han |
collection | PubMed |
description | OBJECTIVES: To investigate the effect of corneal stromal pocket irrigation after small-incision lenticule extraction (SMILE) on visual acuity, intraocular pressure (IOP), corneal parameters and complications after surgery. METHODS: A total of 242 eyes of 121 patients undergoing SMILE were enrolled in this prospective controlled study, and it was designed for one eye to randomly undergo SMILE with balanced salt solution irrigation of the corneal stromal pocket, while the other eye was not. The uncorrected distance visual acuity (UDVA) and slit lamp examination were recorded at 1 hour, 1 day, 1 week, and 1 month. Postoperative corneal density, corneal biomechanical, corneal endothelial cell number, and anterior OCT images were compared at 1 day, 1 week, and 1 month. RESULTS: Compared with the nonirrigation group, the irrigation group showed significantly higher UDVA at 1 day postoperatively (P < 0.05), but there was no significant difference during the rest of the postoperative period (1 hour, 1 week, and 1 month). In addition, no significant differences were found in IOP, corneal density, corneal biomechanics, corneal endothelial cells, and corneal morphology. No visual decline or severe postoperative complications were found in the patients in this study. CONCLUSIONS: Interlamellar irrigation did not affect IOP, corneal parameters, morphology, complications, or UDVA at 1 hour, 1 week, and 1 month after the operation, but it may promote UDVA 1 day after the operation. |
format | Online Article Text |
id | pubmed-7784961 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-77849612021-01-14 Effect of corneal stromal pocket irrigation in small-incision lenticule extraction Wang, Han Ding, Hui Ouyang, Bo-wen Yang, Zhenduo Zhong, Tan Fan, Hongming Zhong, Xingwu Eye (Lond) Article OBJECTIVES: To investigate the effect of corneal stromal pocket irrigation after small-incision lenticule extraction (SMILE) on visual acuity, intraocular pressure (IOP), corneal parameters and complications after surgery. METHODS: A total of 242 eyes of 121 patients undergoing SMILE were enrolled in this prospective controlled study, and it was designed for one eye to randomly undergo SMILE with balanced salt solution irrigation of the corneal stromal pocket, while the other eye was not. The uncorrected distance visual acuity (UDVA) and slit lamp examination were recorded at 1 hour, 1 day, 1 week, and 1 month. Postoperative corneal density, corneal biomechanical, corneal endothelial cell number, and anterior OCT images were compared at 1 day, 1 week, and 1 month. RESULTS: Compared with the nonirrigation group, the irrigation group showed significantly higher UDVA at 1 day postoperatively (P < 0.05), but there was no significant difference during the rest of the postoperative period (1 hour, 1 week, and 1 month). In addition, no significant differences were found in IOP, corneal density, corneal biomechanics, corneal endothelial cells, and corneal morphology. No visual decline or severe postoperative complications were found in the patients in this study. CONCLUSIONS: Interlamellar irrigation did not affect IOP, corneal parameters, morphology, complications, or UDVA at 1 hour, 1 week, and 1 month after the operation, but it may promote UDVA 1 day after the operation. Nature Publishing Group UK 2020-03-10 2020-12 /pmc/articles/PMC7784961/ /pubmed/32157182 http://dx.doi.org/10.1038/s41433-020-0840-1 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Wang, Han Ding, Hui Ouyang, Bo-wen Yang, Zhenduo Zhong, Tan Fan, Hongming Zhong, Xingwu Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title | Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title_full | Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title_fullStr | Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title_full_unstemmed | Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title_short | Effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
title_sort | effect of corneal stromal pocket irrigation in small-incision lenticule extraction |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7784961/ https://www.ncbi.nlm.nih.gov/pubmed/32157182 http://dx.doi.org/10.1038/s41433-020-0840-1 |
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