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Functional Water Wires Catalyze Long-Range Proton Pumping in the Mammalian Respiratory Complex I

[Image: see text] The respiratory complex I is a gigantic (1 MDa) redox-driven proton pump that reduces the ubiquinone pool and generates proton motive force to power ATP synthesis in mitochondria. Despite resolved molecular structures and biochemical characterization of the enzyme from multiple org...

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Detalles Bibliográficos
Autores principales:	Röpke, Michael, Saura, Patricia, Riepl, Daniel, Pöverlein, Maximilian C., Kaila, Ville R. I.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785131/ https://www.ncbi.nlm.nih.gov/pubmed/33325238 http://dx.doi.org/10.1021/jacs.0c09209

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