Independent genomic polymorphisms in the PknH serine threonine kinase locus during evolution of the Mycobacterium tuberculosis Complex affect virulence and host preference

Species belonging to the Mycobacterium tuberculosis Complex (MTBC) show more than 99% genetic identity but exhibit distinct host preference and virulence. The molecular genetic changes that underly host specificity and infection phenotype within MTBC members have not been fully elucidated. Here, we...

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Detalles Bibliográficos
Autores principales: Mata, Elena, Farrell, Damien, Ma, Ruoyao, Uranga, Santiago, Gomez, Ana Belen, Monzon, Marta, Badiola, Juan, Anel, Alberto, Gonzalo-Asensio, Jesús, Martin, Carlos, Gordon, Stephen V., Aguilo, Nacho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785237/
https://www.ncbi.nlm.nih.gov/pubmed/33347499
http://dx.doi.org/10.1371/journal.ppat.1009061

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785237/
https://www.ncbi.nlm.nih.gov/pubmed/33347499
http://dx.doi.org/10.1371/journal.ppat.1009061

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