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Simple models including energy and spike constraints reproduce complex activity patterns and metabolic disruptions

In this work, we introduce new phenomenological neuronal models (eLIF and mAdExp) that account for energy supply and demand in the cell as well as the inactivation of spike generation how these interact with subthreshold and spiking dynamics. Including these constraints, the new models reproduce a b...

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Detalles Bibliográficos
Autores principales: Fardet, Tanguy, Levina, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785241/
https://www.ncbi.nlm.nih.gov/pubmed/33347433
http://dx.doi.org/10.1371/journal.pcbi.1008503

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