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Simple models including energy and spike constraints reproduce complex activity patterns and metabolic disruptions
In this work, we introduce new phenomenological neuronal models (eLIF and mAdExp) that account for energy supply and demand in the cell as well as the inactivation of spike generation how these interact with subthreshold and spiking dynamics. Including these constraints, the new models reproduce a b...
Autores principales: | Fardet, Tanguy, Levina, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785241/ https://www.ncbi.nlm.nih.gov/pubmed/33347433 http://dx.doi.org/10.1371/journal.pcbi.1008503 |
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