Pharmacotherapeutics of SARS-CoV-2 Infections

The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effe...

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Autores principales: Kevadiya, Bhavesh D., Machhi, Jatin, Herskovitz, Jonathan, Oleynikov, Maxim D., Blomberg, Wilson R., Bajwa, Neha, Soni, Dhruvkumar, Das, Srijanee, Hasan, Mahmudul, Patel, Milankumar, Senan, Ahmed M., Gorantla, Santhi, McMillan, JoEllyn, Edagwa, Benson, Eisenberg, Robert, Gurumurthy, Channabasavaiah B., Reid, St Patrick M., Punyadeera, Chamindie, Chang, Linda, Gendelman, Howard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Invited Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785334/
https://www.ncbi.nlm.nih.gov/pubmed/33403500
http://dx.doi.org/10.1007/s11481-020-09968-x
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author Kevadiya, Bhavesh D.
Machhi, Jatin
Herskovitz, Jonathan
Oleynikov, Maxim D.
Blomberg, Wilson R.
Bajwa, Neha
Soni, Dhruvkumar
Das, Srijanee
Hasan, Mahmudul
Patel, Milankumar
Senan, Ahmed M.
Gorantla, Santhi
McMillan, JoEllyn
Edagwa, Benson
Eisenberg, Robert
Gurumurthy, Channabasavaiah B.
Reid, St Patrick M.
Punyadeera, Chamindie
Chang, Linda
Gendelman, Howard E.
author_facet Kevadiya, Bhavesh D.
Machhi, Jatin
Herskovitz, Jonathan
Oleynikov, Maxim D.
Blomberg, Wilson R.
Bajwa, Neha
Soni, Dhruvkumar
Das, Srijanee
Hasan, Mahmudul
Patel, Milankumar
Senan, Ahmed M.
Gorantla, Santhi
McMillan, JoEllyn
Edagwa, Benson
Eisenberg, Robert
Gurumurthy, Channabasavaiah B.
Reid, St Patrick M.
Punyadeera, Chamindie
Chang, Linda
Gendelman, Howard E.
author_sort Kevadiya, Bhavesh D.
collection PubMed
description The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effective treatment options have emerged and now include repurposed antivirals, corticosteroids and virus-specific antibodies. The latter has included convalescence plasma and monoclonal antibodies. Complete viral eradication will be achieved through an effective, safe and preventative vaccine. To now provide a comprehensive summary for each of the pharmacotherapeutics and preventative strategies being offered or soon to be developed for SARS-CoV-2. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-77853342021-01-06 Pharmacotherapeutics of SARS-CoV-2 Infections Kevadiya, Bhavesh D. Machhi, Jatin Herskovitz, Jonathan Oleynikov, Maxim D. Blomberg, Wilson R. Bajwa, Neha Soni, Dhruvkumar Das, Srijanee Hasan, Mahmudul Patel, Milankumar Senan, Ahmed M. Gorantla, Santhi McMillan, JoEllyn Edagwa, Benson Eisenberg, Robert Gurumurthy, Channabasavaiah B. Reid, St Patrick M. Punyadeera, Chamindie Chang, Linda Gendelman, Howard E. J Neuroimmune Pharmacol Invited Review The COVID-19 pandemic has affected more than 38 million people world-wide by person to person transmission of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Therapeutic and preventative strategies for SARS-CoV-2 remains a significant challenge. Within the past several months, effective treatment options have emerged and now include repurposed antivirals, corticosteroids and virus-specific antibodies. The latter has included convalescence plasma and monoclonal antibodies. Complete viral eradication will be achieved through an effective, safe and preventative vaccine. To now provide a comprehensive summary for each of the pharmacotherapeutics and preventative strategies being offered or soon to be developed for SARS-CoV-2. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2021-01-06 2021 /pmc/articles/PMC7785334/ /pubmed/33403500 http://dx.doi.org/10.1007/s11481-020-09968-x Text en © Springer Science+Business Media, LLC, part of Springer Nature 2021 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Invited Review
Kevadiya, Bhavesh D.
Machhi, Jatin
Herskovitz, Jonathan
Oleynikov, Maxim D.
Blomberg, Wilson R.
Bajwa, Neha
Soni, Dhruvkumar
Das, Srijanee
Hasan, Mahmudul
Patel, Milankumar
Senan, Ahmed M.
Gorantla, Santhi
McMillan, JoEllyn
Edagwa, Benson
Eisenberg, Robert
Gurumurthy, Channabasavaiah B.
Reid, St Patrick M.
Punyadeera, Chamindie
Chang, Linda
Gendelman, Howard E.
Pharmacotherapeutics of SARS-CoV-2 Infections
title Pharmacotherapeutics of SARS-CoV-2 Infections
title_full Pharmacotherapeutics of SARS-CoV-2 Infections
title_fullStr Pharmacotherapeutics of SARS-CoV-2 Infections
title_full_unstemmed Pharmacotherapeutics of SARS-CoV-2 Infections
title_short Pharmacotherapeutics of SARS-CoV-2 Infections
title_sort pharmacotherapeutics of sars-cov-2 infections
topic Invited Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785334/
https://www.ncbi.nlm.nih.gov/pubmed/33403500
http://dx.doi.org/10.1007/s11481-020-09968-x
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