Cargando…
Older Molecular Brain Age in Severe Mental Illness
Psychiatric disorders are associated with accelerated aging and enhanced risk for neurodegenerative disorders. Brain aging is associated with molecular, cellular and structural changes that are robust on the group-level, yet show substantial inter-individual variability. Here we assessed deviations...
Autores principales: | Lin, Chien-Wei, Chang, Lun-Ching, Ma, Tianzhou, Oh, Hyunjung, French, Beverly, Puralewski, Rachel, Mathews, Fasil, Fang, Yusi, Lewis, David A., Kennedy, James L., Mueller, Daniel, Marshe, Victoria S., Jaffe, Andrew, Chen, Qiang, Ursini, Gianluca, Weinberger, Daniel, Newman, Anne B., Lenze, Eric J., Nikolova, Yuliya S., Tseng, George C., Sibille, Etienne |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785531/ https://www.ncbi.nlm.nih.gov/pubmed/32632206 http://dx.doi.org/10.1038/s41380-020-0834-1 |
Ejemplares similares
-
FRAS1-related extracellular matrix 3 (FREM3) single-nucleotide polymorphism effects on gene expression, amygdala reactivity and perceptual processing speed: An accelerated aging pathway of depression risk
por: Nikolova, Yuliya S., et al.
Publicado: (2015) -
Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes
por: French, Leon, et al.
Publicado: (2017) -
The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species
por: Seney, Marianne L., et al.
Publicado: (2013) -
DNA methylation in the human frontal cortex reveals a putative mechanism for age-by-disease interactions
por: McKinney, Brandon C., et al.
Publicado: (2019) -
A Conserved BDNF, Glutamate- and GABA-Enriched Gene Module Related to Human Depression Identified by Coexpression Meta-Analysis and DNA Variant Genome-Wide Association Studies
por: Chang, Lun-Ching, et al.
Publicado: (2014)