Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy

Nasopharyngeal cancer (NPC), endemic in Southeast Asia, lacks effective diagnostic and therapeutic strategies. Even in high-income countries the 5-year survival rate for stage IV NPC is less than 40%. Here we report high somatostatin receptor 2 (SSTR2) expression in multiple clinical cohorts compris...

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Autores principales: Lechner, Matt, Schartinger, Volker H., Steele, Christopher D., Nei, Wen Long, Ooft, Marc Lucas, Schreiber, Liesa-Marie, Pipinikas, Christodoulos P., Chung, Grace Tin-Yun, Chan, Yuk Yu, Wu, Feng, To, Ka-Fai, Tsang, Chi Man, Pearce, Wayne, Morelli, Daniele, Philpott, Martin, Masterson, Liam, Nibhani, Reshma, Wells, Graham, Bell, Christopher G., Koller, Julia, Delecluse, Susanne, Yip, Yim Ling, Liu, Jacklyn, Forde, Cillian T., Forster, Martin D., Jay, Amrita, Dudás, József, Krapp, Annika, Wan, Simon, Uprimny, Christian, Sprung, Susanne, Haybaeck, Johannes, Fenton, Tim R., Chester, Kerry, Thirlwell, Christina, Royle, Gary, Marafioti, Teresa, Gupta, Rajeev, Indrasari, Sagung Rai, Herdini, Camelia, Slim, Mohd Afiq Mohd, Indrawati, I., Sutton, Liam, Fles, Renske, Tan, Bing, Yeong, Joe, Jain, Amit, Han, Shuting, Wang, Haitao, Loke, Kelvin S. H., He, Wan, Xu, Ruilian, Jin, Hongtao, Cheng, Zhiqiang, Howard, David, Hwang, Peter H., Le, Quynh-Thu, Tay, Joshua K., West, Robert B., Tsao, Sai Wah, Meyer, Tim, Riechelmann, Herbert, Oppermann, Udo, Delecluse, Henri-Jacques, Willems, Stefan M., Chua, Melvin L. K., Busson, Pierre, Lo, Kwok Wai, Wollmann, Guido, Pillay, Nischalan, Vanhaesebroeck, Bart, Lund, Valerie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785735/
https://www.ncbi.nlm.nih.gov/pubmed/33402692
http://dx.doi.org/10.1038/s41467-020-20308-8

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