Cargando…
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but th...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785811/ https://www.ncbi.nlm.nih.gov/pubmed/33424598 http://dx.doi.org/10.3389/fphar.2020.588384 |
_version_ | 1783632500975730688 |
---|---|
author | Montesel, Andrea Bucolo, Claudio Mouvet, Victoria Moret, Emmanuelle Eandi, Chiara M. |
author_facet | Montesel, Andrea Bucolo, Claudio Mouvet, Victoria Moret, Emmanuelle Eandi, Chiara M. |
author_sort | Montesel, Andrea |
collection | PubMed |
description | We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system. |
format | Online Article Text |
id | pubmed-7785811 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77858112021-01-07 Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient Montesel, Andrea Bucolo, Claudio Mouvet, Victoria Moret, Emmanuelle Eandi, Chiara M. Front Pharmacol Pharmacology We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system. Frontiers Media S.A. 2020-12-23 /pmc/articles/PMC7785811/ /pubmed/33424598 http://dx.doi.org/10.3389/fphar.2020.588384 Text en Copyright © 2020 Montesel, Bucolo, Mouvet, Moret and Eandi http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Pharmacology Montesel, Andrea Bucolo, Claudio Mouvet, Victoria Moret, Emmanuelle Eandi, Chiara M. Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title_full | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title_fullStr | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title_full_unstemmed | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title_short | Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient |
title_sort | case report: central retinal artery occlusion in a covid-19 patient |
topic | Pharmacology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785811/ https://www.ncbi.nlm.nih.gov/pubmed/33424598 http://dx.doi.org/10.3389/fphar.2020.588384 |
work_keys_str_mv | AT monteselandrea casereportcentralretinalarteryocclusioninacovid19patient AT bucoloclaudio casereportcentralretinalarteryocclusioninacovid19patient AT mouvetvictoria casereportcentralretinalarteryocclusioninacovid19patient AT moretemmanuelle casereportcentralretinalarteryocclusioninacovid19patient AT eandichiaram casereportcentralretinalarteryocclusioninacovid19patient |