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Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient

We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but th...

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Autores principales: Montesel, Andrea, Bucolo, Claudio, Mouvet, Victoria, Moret, Emmanuelle, Eandi, Chiara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785811/
https://www.ncbi.nlm.nih.gov/pubmed/33424598
http://dx.doi.org/10.3389/fphar.2020.588384
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author Montesel, Andrea
Bucolo, Claudio
Mouvet, Victoria
Moret, Emmanuelle
Eandi, Chiara M.
author_facet Montesel, Andrea
Bucolo, Claudio
Mouvet, Victoria
Moret, Emmanuelle
Eandi, Chiara M.
author_sort Montesel, Andrea
collection PubMed
description We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system.
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spelling pubmed-77858112021-01-07 Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient Montesel, Andrea Bucolo, Claudio Mouvet, Victoria Moret, Emmanuelle Eandi, Chiara M. Front Pharmacol Pharmacology We report a case of central retinal artery occlusion (CRAO) in a patient with a previous history of severe COVID-19 disease. This disease has been associated with inflammatory-induced homeostasis changes leading to endothelial dysfunction and a procoagulant state with multi-organ involvement, but the burden of thromboembolic complications in COVID-19 patients is currently unknown. The pathogenesis of retinal artery occlusions is a multifactorial process where inflammation and hypercoagulation state are established risk factors. Even if our experience may represent a coincidental relationship, it is likely that COVID-19 patients could be at risk of developing retinal vascular occlusions. A focused ophthalmological surveillance is advisable to prevent and manage this possible cause of severe vision loss that has an important impact in health care system. Frontiers Media S.A. 2020-12-23 /pmc/articles/PMC7785811/ /pubmed/33424598 http://dx.doi.org/10.3389/fphar.2020.588384 Text en Copyright © 2020 Montesel, Bucolo, Mouvet, Moret and Eandi http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Montesel, Andrea
Bucolo, Claudio
Mouvet, Victoria
Moret, Emmanuelle
Eandi, Chiara M.
Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title_full Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title_fullStr Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title_full_unstemmed Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title_short Case Report: Central Retinal Artery Occlusion in a COVID-19 Patient
title_sort case report: central retinal artery occlusion in a covid-19 patient
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785811/
https://www.ncbi.nlm.nih.gov/pubmed/33424598
http://dx.doi.org/10.3389/fphar.2020.588384
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