Single Domain Antibodies Targeting Receptor Binding Pockets of NadA Restrain Adhesion of Neisseria meningitidis to Human Brain Microvascular Endothelial Cells

Neisseria adhesin A (NadA), one of the surface adhesins of Neisseria meningitides (NM), interacts with several cell types including human brain microvascular endothelial cells (hBMECs) and play important role in the pathogenesis. Receptor binding pockets of NadA are localized on the globular head do...

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Detalles Bibliográficos
Autores principales: Kulkarni, Amod, Mochnáčová, Evelína, Majerova, Petra, Čurlík, Ján, Bhide, Katarína, Mertinková, Patrícia, Bhide, Mangesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785856/
https://www.ncbi.nlm.nih.gov/pubmed/33425985
http://dx.doi.org/10.3389/fmolb.2020.573281

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