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RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans

Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarc...

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Autores principales: Jin, Qiangguo, Meng, Zhaopeng, Sun, Changming, Cui, Hui, Su, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785874/
https://www.ncbi.nlm.nih.gov/pubmed/33425871
http://dx.doi.org/10.3389/fbioe.2020.605132
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author Jin, Qiangguo
Meng, Zhaopeng
Sun, Changming
Cui, Hui
Su, Ran
author_facet Jin, Qiangguo
Meng, Zhaopeng
Sun, Changming
Cui, Hui
Su, Ran
author_sort Jin, Qiangguo
collection PubMed
description Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarchical features. However, few studies investigate 3D networks for liver tumor segmentation. In this paper, we propose a 3D hybrid residual attention-aware segmentation method, i.e., RA-UNet, to precisely extract the liver region and segment tumors from the liver. The proposed network has a basic architecture as U-Net which extracts contextual information combining low-level feature maps with high-level ones. Attention residual modules are integrated so that the attention-aware features change adaptively. This is the first work that an attention residual mechanism is used to segment tumors from 3D medical volumetric images. We evaluated our framework on the public MICCAI 2017 Liver Tumor Segmentation dataset and tested the generalization on the 3DIRCADb dataset. The experiments show that our architecture obtains competitive results.
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spelling pubmed-77858742021-01-07 RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans Jin, Qiangguo Meng, Zhaopeng Sun, Changming Cui, Hui Su, Ran Front Bioeng Biotechnol Bioengineering and Biotechnology Automatic extraction of liver and tumor from CT volumes is a challenging task due to their heterogeneous and diffusive shapes. Recently, 2D deep convolutional neural networks have become popular in medical image segmentation tasks because of the utilization of large labeled datasets to learn hierarchical features. However, few studies investigate 3D networks for liver tumor segmentation. In this paper, we propose a 3D hybrid residual attention-aware segmentation method, i.e., RA-UNet, to precisely extract the liver region and segment tumors from the liver. The proposed network has a basic architecture as U-Net which extracts contextual information combining low-level feature maps with high-level ones. Attention residual modules are integrated so that the attention-aware features change adaptively. This is the first work that an attention residual mechanism is used to segment tumors from 3D medical volumetric images. We evaluated our framework on the public MICCAI 2017 Liver Tumor Segmentation dataset and tested the generalization on the 3DIRCADb dataset. The experiments show that our architecture obtains competitive results. Frontiers Media S.A. 2020-12-23 /pmc/articles/PMC7785874/ /pubmed/33425871 http://dx.doi.org/10.3389/fbioe.2020.605132 Text en Copyright © 2020 Jin, Meng, Sun, Cui and Su. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Bioengineering and Biotechnology
Jin, Qiangguo
Meng, Zhaopeng
Sun, Changming
Cui, Hui
Su, Ran
RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title_full RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title_fullStr RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title_full_unstemmed RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title_short RA-UNet: A Hybrid Deep Attention-Aware Network to Extract Liver and Tumor in CT Scans
title_sort ra-unet: a hybrid deep attention-aware network to extract liver and tumor in ct scans
topic Bioengineering and Biotechnology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785874/
https://www.ncbi.nlm.nih.gov/pubmed/33425871
http://dx.doi.org/10.3389/fbioe.2020.605132
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