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CRISPR Genome Editing Applied to the Pathogenic Retrovirus HTLV-1

CRISPR editing of retroviral proviruses has been limited to HIV-1. We propose human T-cell leukemia virus type 1 (HTLV-1) as an excellent model to advance CRISPR/Cas9 genome editing technologies against actively expressing and latent retroviral proviruses. HTLV-1 is a tumorigenic human retrovirus re...

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Detalles Bibliográficos
Autores principales:	Panfil, Amanda R., Green, Patrick L., Yoder, Kristine E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785941/ https://www.ncbi.nlm.nih.gov/pubmed/33425776 http://dx.doi.org/10.3389/fcimb.2020.580371

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