Compound C Protects Against Cisplatin-Induced Nephrotoxicity Through Pleiotropic Effects

AICAR (Acadesine/AICA riboside) as an activator of AMPK, can protect renal tubular cells from cisplatin induced apoptosis. But in our experiment, the dorsomorphin (compound C, an inhibitor of AMPK) also significantly reduced cisplatin induced renal tubular cells apoptosis. Accordingly, we tested whe...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Fanghua, Sun, Anbang, Cheng, Genyang, Liu, Dong, Xiao, Jing, Zhao, Zhanzheng, Dong, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7785967/
https://www.ncbi.nlm.nih.gov/pubmed/33424637
http://dx.doi.org/10.3389/fphys.2020.614244

Ejemplares similares

Ejemplares similares