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Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study
BACKGROUND/AIMS: The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking. We aim to evaluate the practice patterns, including i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Neurogastroenterology and Motility
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786091/ https://www.ncbi.nlm.nih.gov/pubmed/32699187 http://dx.doi.org/10.5056/jnm20069 |
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author | Kim, Su Jin Park, Moo In Kim, Gwang Ha Lee, Moon Won Jung, Kyoungwon Lee, Jin Seol, Sang Young Jee, Sam Ryong Lee, Hong Sub Jang, Jin Seok Cha, Jae Hwang |
author_facet | Kim, Su Jin Park, Moo In Kim, Gwang Ha Lee, Moon Won Jung, Kyoungwon Lee, Jin Seol, Sang Young Jee, Sam Ryong Lee, Hong Sub Jang, Jin Seok Cha, Jae Hwang |
author_sort | Kim, Su Jin |
collection | PubMed |
description | BACKGROUND/AIMS: The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking. We aim to evaluate the practice patterns, including initial treatment and response, in the Busan city and Gyeongnam province area. METHODS: We retrospectively reviewed medical records to gain data on patient characteristics, medication, endoscopic images, and esophageal biopsy results. From January 2009 to December 2019, a total of 42 patients were diagnosed with eosinophilic esophagitis. RESULTS: The mean age was 50.7 (from 22 to 81) years and the cohort was predominantly male (78.6%, 33/42). The proton pump inhibitor was the preferred treatment as an initial trial for 64.3% (27/42) of patients, followed by swallowed topical steroids (16.7%, 7/42). Clinical improvement after proton pump inhibitor therapy was achieved in 88.9% (24/27) of patients. Two patients who did not achieve improvement showed a clinical and endoscopic response after swallowed topical steroids treatment. No patient received diet elimination or balloon dilatation therapy. CONCLUSIONS: The treatment response of eosinophilic esophagitis was good in Busan city and Gyeongnam province area in Korea. Proton pump inhibitor therapy was the preferred and most effective treatment for eosinophilic esophagitis as the initial therapy. |
format | Online Article Text |
id | pubmed-7786091 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Society of Neurogastroenterology and Motility |
record_format | MEDLINE/PubMed |
spelling | pubmed-77860912021-01-30 Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study Kim, Su Jin Park, Moo In Kim, Gwang Ha Lee, Moon Won Jung, Kyoungwon Lee, Jin Seol, Sang Young Jee, Sam Ryong Lee, Hong Sub Jang, Jin Seok Cha, Jae Hwang J Neurogastroenterol Motil Original Article BACKGROUND/AIMS: The prevalence of eosinophilic esophagitis is increasing in Korea and there are few single-center studies regarding eosinophilic esophagitis in Korea. In particular, data about management for eosinophilic esophagitis are lacking. We aim to evaluate the practice patterns, including initial treatment and response, in the Busan city and Gyeongnam province area. METHODS: We retrospectively reviewed medical records to gain data on patient characteristics, medication, endoscopic images, and esophageal biopsy results. From January 2009 to December 2019, a total of 42 patients were diagnosed with eosinophilic esophagitis. RESULTS: The mean age was 50.7 (from 22 to 81) years and the cohort was predominantly male (78.6%, 33/42). The proton pump inhibitor was the preferred treatment as an initial trial for 64.3% (27/42) of patients, followed by swallowed topical steroids (16.7%, 7/42). Clinical improvement after proton pump inhibitor therapy was achieved in 88.9% (24/27) of patients. Two patients who did not achieve improvement showed a clinical and endoscopic response after swallowed topical steroids treatment. No patient received diet elimination or balloon dilatation therapy. CONCLUSIONS: The treatment response of eosinophilic esophagitis was good in Busan city and Gyeongnam province area in Korea. Proton pump inhibitor therapy was the preferred and most effective treatment for eosinophilic esophagitis as the initial therapy. The Korean Society of Neurogastroenterology and Motility 2021-01-30 2021-01-30 /pmc/articles/PMC7786091/ /pubmed/32699187 http://dx.doi.org/10.5056/jnm20069 Text en © 2021 The Korean Society of Neurogastroenterology and Motility This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Kim, Su Jin Park, Moo In Kim, Gwang Ha Lee, Moon Won Jung, Kyoungwon Lee, Jin Seol, Sang Young Jee, Sam Ryong Lee, Hong Sub Jang, Jin Seok Cha, Jae Hwang Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title | Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title_full | Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title_fullStr | Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title_full_unstemmed | Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title_short | Practice Patterns for Eosinophilic Esophagitis Patients in Busan and Gyeongnam: A Korean Multicenter Database Study |
title_sort | practice patterns for eosinophilic esophagitis patients in busan and gyeongnam: a korean multicenter database study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786091/ https://www.ncbi.nlm.nih.gov/pubmed/32699187 http://dx.doi.org/10.5056/jnm20069 |
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