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THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle

The phenotype of carcass traits in beef cattle are affected by random genetic and non-genetic effects, which both can be modulated by an environmental variable such as Temperature-Humidity Index (THI), a key environmental factor in cattle production. In this study, a multivariate reaction norm model...

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Autores principales: Chung, Yoonji, Lee, Seung Hwan, Lee, Hak-Kyo, Lim, Dajeong, van der Werf, Julius, Lee, S. Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786192/
https://www.ncbi.nlm.nih.gov/pubmed/33424920
http://dx.doi.org/10.3389/fgene.2020.576377
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author Chung, Yoonji
Lee, Seung Hwan
Lee, Hak-Kyo
Lim, Dajeong
van der Werf, Julius
Lee, S. Hong
author_facet Chung, Yoonji
Lee, Seung Hwan
Lee, Hak-Kyo
Lim, Dajeong
van der Werf, Julius
Lee, S. Hong
author_sort Chung, Yoonji
collection PubMed
description The phenotype of carcass traits in beef cattle are affected by random genetic and non-genetic effects, which both can be modulated by an environmental variable such as Temperature-Humidity Index (THI), a key environmental factor in cattle production. In this study, a multivariate reaction norm model (MRNM) was used to assess if the random genetic and non-genetic (i.e., residual) effects of carcass weight (CW), back fat thickness (BFT), eye muscle area (EMA), and marbling score (MS) were modulated by THI, using 9,318 Hanwoo steers (N = 8,964) and cows (N = 354) that were genotyped on the Illumina Bovine SNP50 BeadChip (50K). THI was measured based on the period of 15–45 days before slaughter. Both the correlation and the interaction between THI and random genetic and non-genetic effects were accounted for in the model. In the analyses, it was shown that the genetic effects of EMA and the non-genetic effects of CW and MS were significantly modulated by THI. No significant THI modulation of such effects was found for BFT. These results highlight the relevance of THI changes for the genetic and non-genetic variation of CW, EMA, and MS in Hanwoo beef cattle. Importantly, heritability estimates for CW, EMA, and MS from additive models without considering THI interactions were underestimated. Moreover, the significance of interaction can be biased if not properly accounting for the correlation between THI and genetic and non-genetic effects. Thus, we argue that the estimation of genetic parameters should be based on appropriate models to avoid any potential bias of estimates. Our finding should serve as a basis for future studies aiming at revealing genotype by environment interaction in estimation and genomic prediction of breeding values.
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spelling pubmed-77861922021-01-07 THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle Chung, Yoonji Lee, Seung Hwan Lee, Hak-Kyo Lim, Dajeong van der Werf, Julius Lee, S. Hong Front Genet Genetics The phenotype of carcass traits in beef cattle are affected by random genetic and non-genetic effects, which both can be modulated by an environmental variable such as Temperature-Humidity Index (THI), a key environmental factor in cattle production. In this study, a multivariate reaction norm model (MRNM) was used to assess if the random genetic and non-genetic (i.e., residual) effects of carcass weight (CW), back fat thickness (BFT), eye muscle area (EMA), and marbling score (MS) were modulated by THI, using 9,318 Hanwoo steers (N = 8,964) and cows (N = 354) that were genotyped on the Illumina Bovine SNP50 BeadChip (50K). THI was measured based on the period of 15–45 days before slaughter. Both the correlation and the interaction between THI and random genetic and non-genetic effects were accounted for in the model. In the analyses, it was shown that the genetic effects of EMA and the non-genetic effects of CW and MS were significantly modulated by THI. No significant THI modulation of such effects was found for BFT. These results highlight the relevance of THI changes for the genetic and non-genetic variation of CW, EMA, and MS in Hanwoo beef cattle. Importantly, heritability estimates for CW, EMA, and MS from additive models without considering THI interactions were underestimated. Moreover, the significance of interaction can be biased if not properly accounting for the correlation between THI and genetic and non-genetic effects. Thus, we argue that the estimation of genetic parameters should be based on appropriate models to avoid any potential bias of estimates. Our finding should serve as a basis for future studies aiming at revealing genotype by environment interaction in estimation and genomic prediction of breeding values. Frontiers Media S.A. 2020-12-23 /pmc/articles/PMC7786192/ /pubmed/33424920 http://dx.doi.org/10.3389/fgene.2020.576377 Text en Copyright © 2020 Chung, Lee, Lee, Lim, van der Werf and Lee. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Chung, Yoonji
Lee, Seung Hwan
Lee, Hak-Kyo
Lim, Dajeong
van der Werf, Julius
Lee, S. Hong
THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title_full THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title_fullStr THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title_full_unstemmed THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title_short THI Modulation of Genetic and Non-genetic Variance Components for Carcass Traits in Hanwoo Cattle
title_sort thi modulation of genetic and non-genetic variance components for carcass traits in hanwoo cattle
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786192/
https://www.ncbi.nlm.nih.gov/pubmed/33424920
http://dx.doi.org/10.3389/fgene.2020.576377
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