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Expeditious Generation of Biparatopic Common Light Chain Antibodies via Chicken Immunization and Yeast Display Screening
Bispecific (BsAb) and biparatopic (BpAb) antibodies emerged as promising formats for therapeutic biologics exhibiting tailor-made functional properties. Over recent years, chicken-derived antibodies have gained traction for diagnostic and therapeutic applications due to their broad epitope coverage...
Autores principales: | Bogen, Jan P., Carrara, Stefania C., Fiebig, David, Grzeschik, Julius, Hock, Björn, Kolmar, Harald |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786285/ https://www.ncbi.nlm.nih.gov/pubmed/33424853 http://dx.doi.org/10.3389/fimmu.2020.606878 |
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