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Mobilized Multipotent Hematopoietic Progenitors Stabilize and Expand Regulatory T Cells to Protect Against Autoimmune Encephalomyelitis

Achieving immunoregulation via in vivo expansion of Foxp3(+) regulatory CD4(+) T cells (Treg) remains challenging. We have shown that mobilization confers to multipotent hematopoietic progenitors (MPPs) the capacity to enhance Treg proliferation. Transcriptomic analysis of Tregs co-cultured with MPP...

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Detalles Bibliográficos
Autores principales:	Korniotis, Sarantis, D’Aveni, Maud, Hergalant, Sébastien, Letscher, Hélène, Tejerina, Emmanuel, Gastineau, Pauline, Agbogan, Viviane A., Gras, Christophe, Fouquet, Guillemette, Rossignol, Julien, Chèvre, Jean-Claude, Cagnard, Nicolas, Rubio, Marie-Thérèse, Hermine, Olivier, Zavala, Flora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786289/ https://www.ncbi.nlm.nih.gov/pubmed/33424854 http://dx.doi.org/10.3389/fimmu.2020.607175

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