Cargando…

In silico investigation of saponins and tannins as potential inhibitors of SARS-CoV-2 main protease (M(pro))

It is no longer news that a novel strain of coronavirus named SARS-CoV-2 is ravaging the health sector worldwide, several attempts have been made to curtail this pandemic via repurposing of old drugs but at the present, available drugs are not adequately effective. Over the years, plant phytochemica...

Descripción completa

Detalles Bibliográficos
Autores principales:	Falade, Victoria Adeola, Adelusi, Temitope Isaac, Adedotun, Ibrahim Olaide, Abdul-Hammed, Misbaudeen, Lawal, Teslim Alabi, Agboluaje, Saheed Alabi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786323/ https://www.ncbi.nlm.nih.gov/pubmed/33425648 http://dx.doi.org/10.1007/s40203-020-00071-w

Ejemplares similares

Target-based drug discovery, ADMET profiling and bioactivity studies of antibiotics as potential inhibitors of SARS-CoV-2 main protease (M(pro))
por: Abdul-Hammed, Misbaudeen, et al.
Publicado: (2021)

Molecular dynamics, quantum mechanics and docking studies of some Keap1 inhibitors – An insight into the atomistic mechanisms of their antioxidant potential
por: Adelusi, Temitope Isaac, et al.
Publicado: (2021)

Docking covalent targets for drug discovery: stimulating the computer-aided drug design community of possible pitfalls and erroneous practices
por: Oyedele, Abdul-Quddus Kehinde, et al.
Publicado: (2022)

Molecular docking and experimental validation of the effect of ergothioneine on heat shock protein-70 following endurance exercise by Arabian stallions
por: Adah, Adakole Sylvanus, et al.
Publicado: (2023)

Psychological resilience moderates influence of depression on sleep dysfunction of people living with diabetes
por: Wojujutari, Ajele Kenni, et al.
Publicado: (2019)

Spiritual intelligence, mindfulness, emotional dysregulation, depression relationship with mental well-being among persons with diabetes during COVID-19 pandemic
por: Ajele, Wojujutari Kenni, et al.
Publicado: (2021)

Relationship between depression and psychological well-being among persons with diabetes during COVID-19 pandemic: diabetes distress as a mediator
por: Ajele, Wojujutari Kenni, et al.
Publicado: (2022)

Dietary polyphenols mitigate SARS-CoV-2 main protease (Mpro)–Molecular dynamics, molecular mechanics, and density functional theory investigations
por: Adelusi, Temitope Isaac, et al.
Publicado: (2022)

In-silico analysis of the inhibition of the SARS-CoV-2 main protease by some active compounds from selected African plants
por: Umar, Haruna I., et al.
Publicado: (2021)

Diphenyl Diselenide and SARS-CoV-2: in silico Exploration of the Mechanisms of Inhibition of Main Protease (M(pro)) and Papain-like Protease (PL(pro))
por: Omage, Folorunsho Bright, et al.
Publicado: (2023)

In silico analysis of selected alkaloids against main protease (M(pro)) of SARS-CoV-2
por: Garg, Saksham, et al.
Publicado: (2020)

In silico approach for identification of natural compounds as potential COVID 19 main protease (M(pro)) inhibitors
por: Chaturvedi, Monika, et al.
Publicado: (2021)

An in-silico evaluation of COVID-19 main protease with clinically approved drugs
por: Tachoua, Wafa, et al.
Publicado: (2020)

Statins and the COVID-19 main protease: in silico evidence on direct interaction
por: Reiner, Željko, et al.
Publicado: (2020)

Novel Molecules derived from 3-O-(6-galloylglucoside) inhibit Main Protease of SARS-CoV 2 In Silico
por: Umar, Haruna Isiyaku, et al.
Publicado: (2021)

Changes in tannin and saponin components during co-composting of Camellia oleifera Abel shell and seed cake
por: Zhang, Jinping, et al.
Publicado: (2020)

Evaluation of origanum oil, hydrolysable tannins and tea saponin in mitigating ruminant methane: In vitro and in vivo methods
por: Zhang, Fangyu, et al.
Publicado: (2021)

An in-silico investigation of potential natural polyphenols for the targeting of COVID main protease inhibitor
por: Aljarba, Nada H., et al.
Publicado: (2022)

In silico assessment of diterpenes as potential inhibitors of SARS-COV-2 main protease
por: Abdelrady, Yousef A, et al.
Publicado: (2023)

Normal corneal endothelial cell density in Nigerians
por: Ewete, Temitope, et al.
Publicado: (2016)

In silico analysis of echinocandins binding to the main proteases of coronaviruses PEDV (3CL(pro)) and SARS-CoV-2 (M(pro))
por: Vergoten, Gérard, et al.
Publicado: (2021)

In Silico Substrate-Binding Profiling for SARS-CoV-2 Main Protease (M(pro)) Using Hexapeptide Substrates
por: Zabo, Sophakama, et al.
Publicado: (2023)

Changes of Microbial Population in the Rumen of Dairy Steers as Influenced by Plant Containing Tannins and Saponins and Roughage to Concentrate Ratio
por: Anantasook, N., et al.
Publicado: (2013)

In-silico screening of naturally derived phytochemicals against SARS-CoV Main protease
por: Mostafa, Islam, et al.
Publicado: (2021)

Acridone Alkaloids: In-Silico Investigation Against SARS-CoV-2 Main Protease
por: Oderinlo, Ogunyemi Olajide, et al.
Publicado: (2022)

In Silico Evaluation of the Effectivity of Approved Protease Inhibitors against the Main Protease of the Novel SARS-CoV-2 Virus
por: Eleftheriou, Phaedra, et al.
Publicado: (2020)

Inhibition of Key Enzymes Linked to Type 2 Diabetes and Sodium Nitroprusside Induced Lipid Peroxidation in Rats’ Pancreas by Phenolic Extracts of Avocado Pear Leaves and Fruit
por: Oboh, Ganiyu, et al.
Publicado: (2014)

Synthesis, characterization and application of novel 1, 3-bis[(furan-2-l)methylene]thiourea functional dye on wool and cotton fabrics
por: Jabar, J. M., et al.
Publicado: (2020)

In Silico Mining of Terpenes from Red-Sea Invertebrates for SARS-CoV-2 Main Protease (M(pro)) Inhibitors
por: Ibrahim, Mahmoud A. A., et al.
Publicado: (2021)

Inhibitory effects of selected isoquinoline alkaloids against main protease (M(pro)) of SARS-CoV-2, in silico study
por: Sadeghi, Morteza, et al.
Publicado: (2022)

In vitro and in silico studies of SARS-CoV-2 main protease M(pro) inhibitors isolated from Helichrysum bracteatum
por: Wahab, Gehad Abdel, et al.
Publicado: (2022)

Combination Effects of Plant Extracts Rich in Tannins and Saponins as Feed Additives for Mitigating in Vitro Ruminal Methane and Ammonia Formation
por: Jayanegara, Anuraga, et al.
Publicado: (2020)

Impact of Drug Repurposing on SARS-Cov-2 Main Protease
por: Ndagi, Umar, et al.
Publicado: (2023)

Hordatines as a Potential Inhibitor of COVID-19 Main Protease and RNA Polymerase: An In-Silico Approach
por: Dahab, Mohammed A., et al.
Publicado: (2020)

Recognition of Natural Products as Potential Inhibitors of COVID-19 Main Protease (Mpro): In-Silico Evidences
por: Narkhede, Rohan R., et al.
Publicado: (2020)

In silico targeting SARS-CoV-2 spike protein and main protease by biochemical compounds
por: Babaeekhou, Laleh, et al.
Publicado: (2021)

2-Phenoxyacetamide derivatives as SARS-CoV-2 main protease inhibitor: In silico studies
por: Hariyono, Pandu, et al.
Publicado: (2022)

Apigenin analogues as SARS-CoV-2 main protease inhibitors: In-silico screening approach
por: Farhat, Ameny, et al.
Publicado: (2022)

In silico structure-based discovery of a SARS-CoV-2 main protease inhibitor
por: Wen, Lei, et al.
Publicado: (2021)

In silico evaluation of Philippine Natural Products against SARS-CoV-2 Main Protease
por: Cheng, Adrian Josiah T., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p1u9g8nm62p3bffm8id9f4e0o4