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Knock-Down of Hippocampal DISC1 in Immune-Challenged Mice Impairs the Prefrontal–Hippocampal Coupling and the Cognitive Performance Throughout Development

Disrupted-in-schizophrenia 1 (DISC1) gene represents an intracellular hub of developmental processes. When combined with early environmental stressors, such as maternal immune activation, but not in the absence of thereof, whole-brain DISC1 knock-down leads to memory and executive deficits as result...

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Detalles Bibliográficos
Autores principales: Xu, Xiaxia, Song, Lingzhen, Hanganu-Opatz, Ileana L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786359/
https://www.ncbi.nlm.nih.gov/pubmed/33037815
http://dx.doi.org/10.1093/cercor/bhaa291