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Combined onabotulinumtoxinA/atogepant treatment blocks activation/sensitization of high-threshold and wide-dynamic range neurons
BACKGROUND: OnabotulinumtoxinA and agents that block calcitonin gene‒receptor peptide action have both been found to have anti-migraine effects, but they inhibit different populations of meningeal nociceptors. We therefore tested the effects of combined treatment with onabotulinumtoxinA and the calc...
Autores principales: | Melo-Carrillo, Agustin, Strassman, Andrew M, Schain, Aaron J, Adams, Aubrey Manack, Brin, Mitchell F, Burstein, Rami |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786391/ https://www.ncbi.nlm.nih.gov/pubmed/33200944 http://dx.doi.org/10.1177/0333102420970507 |
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