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Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson’s disease model

BACKGROUND: Cognitive decline occurs frequently in Parkinson’s disease (PD), which greatly decreases the quality of life of patients. However, the mechanisms remain to be investigated. Neuroinflammation mediated by overactivated microglia is a common pathological feature in multiple neurological dis...

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Detalles Bibliográficos
Autores principales: Zhang, Dongdong, Li, Sheng, Hou, Liyan, Jing, Lu, Ruan, Zhengzheng, Peng, Bingjie, Zhang, Xiaomeng, Hong, Jau-Shyong, Zhao, Jie, Wang, Qingshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786472/
https://www.ncbi.nlm.nih.gov/pubmed/33402167
http://dx.doi.org/10.1186/s12974-020-02065-z