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Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry

AIMS: In Danish patients with inflammatory rheumatic diseases to explore self-protection strategies and health behaviour including adherence to disease-modifying antirheumatic treatment (DMARD) during the initial phase of the COVID-19 pandemic and again after the reopening of the society started. Fu...

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Autores principales: Glintborg, Bente, Jensen, Dorte Vendelbo, Engel, Sara, Terslev, Lene, Pfeiffer Jensen, Mogens, Hendricks, Oliver, Østergaard, Mikkel, Horskjær Rasmussen, Simon, Adelsten, Thomas, Colic, Ada, Danebod, Kamilla, Kildemand, Malene, Loft, Anne Gitte, Munk, Heidi Lausten, Pedersen, Jens Kristian, Østgård, René Drage, Møller Sørensen, Christian, Krogh, Niels Steen, Agerbo, Jette, Ziegler, Connie, Hetland, Merete Lund
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786545/
https://www.ncbi.nlm.nih.gov/pubmed/33402443
http://dx.doi.org/10.1136/rmdopen-2020-001505
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author Glintborg, Bente
Jensen, Dorte Vendelbo
Engel, Sara
Terslev, Lene
Pfeiffer Jensen, Mogens
Hendricks, Oliver
Østergaard, Mikkel
Horskjær Rasmussen, Simon
Adelsten, Thomas
Colic, Ada
Danebod, Kamilla
Kildemand, Malene
Loft, Anne Gitte
Munk, Heidi Lausten
Pedersen, Jens Kristian
Østgård, René Drage
Møller Sørensen, Christian
Krogh, Niels Steen
Agerbo, Jette
Ziegler, Connie
Hetland, Merete Lund
author_facet Glintborg, Bente
Jensen, Dorte Vendelbo
Engel, Sara
Terslev, Lene
Pfeiffer Jensen, Mogens
Hendricks, Oliver
Østergaard, Mikkel
Horskjær Rasmussen, Simon
Adelsten, Thomas
Colic, Ada
Danebod, Kamilla
Kildemand, Malene
Loft, Anne Gitte
Munk, Heidi Lausten
Pedersen, Jens Kristian
Østgård, René Drage
Møller Sørensen, Christian
Krogh, Niels Steen
Agerbo, Jette
Ziegler, Connie
Hetland, Merete Lund
author_sort Glintborg, Bente
collection PubMed
description AIMS: In Danish patients with inflammatory rheumatic diseases to explore self-protection strategies and health behaviour including adherence to disease-modifying antirheumatic treatment (DMARD) during the initial phase of the COVID-19 pandemic and again after the reopening of the society started. Furthermore, to identify characteristics of patients with high levels of anxiety and self-isolation. METHODS: Patients in routine care followed prospectively in the nationwide DANBIO registry were invited to answer an online questionnaire regarding disease activity and COVID-19 infection, behaviour in March and June 2020. Responses were linked to patient data in DANBIO. Characteristics potentially associated with anxiety, self-isolation and medication adherence (gender/age/diagnosis/education/work status/comorbidity/DMARD/smoking/EQ-5D/disease activity) were explored with multivariable logistic regression analyses. RESULTS: We included 12 789 patients (8168 rheumatoid arthritis/2068 psoriatic arthritis/1758 axial spondyloarthritis/795 other) of whom 65% were women and 36% treated with biological DMARD. Self-reported COVID-19 prevalence was 0.3%. Patients reported that they were worried to get COVID-19 infection (March/June: 70%/45%) and self-isolated more than others of the same age (48%/38%). The fraction of patients who changed medication due to fear of COVID-19 were 4.1%/0.6%. Female gender, comorbidities, not working, lower education, biological treatment and poor European Quality of life, 5 dimensions were associated with both anxiety and self-isolation. CONCLUSION: In >12 000 patients with inflammatory arthritis, we found widespread anxiety and self-isolation, but high medication adherence, in the initial phase of the COVID-19 pandemic. This persisted during the gradual opening of society during the following months. Attention to patients’ anxiety and self-isolation is important during this and potential future epidemics.
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spelling pubmed-77865452021-01-07 Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry Glintborg, Bente Jensen, Dorte Vendelbo Engel, Sara Terslev, Lene Pfeiffer Jensen, Mogens Hendricks, Oliver Østergaard, Mikkel Horskjær Rasmussen, Simon Adelsten, Thomas Colic, Ada Danebod, Kamilla Kildemand, Malene Loft, Anne Gitte Munk, Heidi Lausten Pedersen, Jens Kristian Østgård, René Drage Møller Sørensen, Christian Krogh, Niels Steen Agerbo, Jette Ziegler, Connie Hetland, Merete Lund RMD Open Miscellaneous AIMS: In Danish patients with inflammatory rheumatic diseases to explore self-protection strategies and health behaviour including adherence to disease-modifying antirheumatic treatment (DMARD) during the initial phase of the COVID-19 pandemic and again after the reopening of the society started. Furthermore, to identify characteristics of patients with high levels of anxiety and self-isolation. METHODS: Patients in routine care followed prospectively in the nationwide DANBIO registry were invited to answer an online questionnaire regarding disease activity and COVID-19 infection, behaviour in March and June 2020. Responses were linked to patient data in DANBIO. Characteristics potentially associated with anxiety, self-isolation and medication adherence (gender/age/diagnosis/education/work status/comorbidity/DMARD/smoking/EQ-5D/disease activity) were explored with multivariable logistic regression analyses. RESULTS: We included 12 789 patients (8168 rheumatoid arthritis/2068 psoriatic arthritis/1758 axial spondyloarthritis/795 other) of whom 65% were women and 36% treated with biological DMARD. Self-reported COVID-19 prevalence was 0.3%. Patients reported that they were worried to get COVID-19 infection (March/June: 70%/45%) and self-isolated more than others of the same age (48%/38%). The fraction of patients who changed medication due to fear of COVID-19 were 4.1%/0.6%. Female gender, comorbidities, not working, lower education, biological treatment and poor European Quality of life, 5 dimensions were associated with both anxiety and self-isolation. CONCLUSION: In >12 000 patients with inflammatory arthritis, we found widespread anxiety and self-isolation, but high medication adherence, in the initial phase of the COVID-19 pandemic. This persisted during the gradual opening of society during the following months. Attention to patients’ anxiety and self-isolation is important during this and potential future epidemics. BMJ Publishing Group 2021-01-05 /pmc/articles/PMC7786545/ /pubmed/33402443 http://dx.doi.org/10.1136/rmdopen-2020-001505 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ http://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.
spellingShingle Miscellaneous
Glintborg, Bente
Jensen, Dorte Vendelbo
Engel, Sara
Terslev, Lene
Pfeiffer Jensen, Mogens
Hendricks, Oliver
Østergaard, Mikkel
Horskjær Rasmussen, Simon
Adelsten, Thomas
Colic, Ada
Danebod, Kamilla
Kildemand, Malene
Loft, Anne Gitte
Munk, Heidi Lausten
Pedersen, Jens Kristian
Østgård, René Drage
Møller Sørensen, Christian
Krogh, Niels Steen
Agerbo, Jette
Ziegler, Connie
Hetland, Merete Lund
Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title_full Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title_fullStr Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title_full_unstemmed Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title_short Self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the COVID-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the Danish DANBIO registry
title_sort self-protection strategies and health behaviour in patients with inflammatory rheumatic diseases during the covid-19 pandemic: results and predictors in more than 12 000 patients with inflammatory rheumatic diseases followed in the danish danbio registry
topic Miscellaneous
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786545/
https://www.ncbi.nlm.nih.gov/pubmed/33402443
http://dx.doi.org/10.1136/rmdopen-2020-001505
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