Long Noncoding RNA TYKRIL Plays a Role in Pulmonary Hypertension via the p53-mediated Regulation of PDGFRβ

Rationale: Long noncoding RNAs (lncRNAs) are emerging as important regulators of diverse biological functions. Their role in pulmonary arterial hypertension (PAH) remains to be explored. Objectives: To elucidate the role of TYKRIL (tyrosine kinase receptor–inducing lncRNA) as a regulator of p53/ PDG...

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Detalles Bibliográficos
Autores principales: Zehendner, Christoph M., Valasarajan, Chanil, Werner, Astrid, Boeckel, Jes-Niels, Bischoff, Florian C., John, David, Weirick, Tyler, Glaser, Simone F., Rossbach, Oliver, Jaé, Nicolas, Demolli, Shemsi, Khassafi, Fatemeh, Yuan, Ke, de Jesus Perez, Vinicio A., Michalik, Katharina M., Chen, Wei, Seeger, Werner, Guenther, Andreas, Wasnick, Roxana M., Uchida, Shizuka, Zeiher, Andreas M., Dimmeler, Stefanie, Pullamsetti, Soni S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786813/
https://www.ncbi.nlm.nih.gov/pubmed/32634060
http://dx.doi.org/10.1164/rccm.201910-2041OC

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