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Brain tissue transcriptomic analysis of SIV-infected macaques identifies several altered metabolic pathways linked to neuropathogenesis and poly (ADP-ribose) polymerases (PARPs) as potential therapeutic targets

Despite improvements in antiretroviral therapy, human immunodeficiency virus type 1 (HIV-1)-associated neurocognitive disorders (HAND) remain prevalent in subjects undergoing therapy. HAND significantly affects individuals’ quality of life, as well as adherence to therapy, and, despite the increasin...

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Detalles Bibliográficos
Autores principales:	Mavian, Carla, Ramirez-Mata, Andrea S., Dollar, James Jarad, Nolan, David J., Cash, Melanie, White, Kevin, Rich, Shannan N., Magalis, Brittany Rife, Marini, Simone, Prosperi, Mattia C. F., Amador, David Moraga, Riva, Alberto, Williams, Kenneth C., Salemi, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7786889/ https://www.ncbi.nlm.nih.gov/pubmed/33405206 http://dx.doi.org/10.1007/s13365-020-00927-z

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