Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study

AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1...

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Detalles Bibliográficos
Autores principales: Wiedmeier, Julia E, Mountjoy, Luke J, Buras, Matthew R, Kosiorek, Heidi E, Coppola, Kyle E, Verona, Patricia M, Cook, Curtiss B, Karlin, Nina J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787137/
https://www.ncbi.nlm.nih.gov/pubmed/33437503
http://dx.doi.org/10.2144/fsoa-2020-0117
Descripción
Sumario:AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan–Meier method. Hemoglobin A(1c) and glucose levels the year after leukemia diagnosis were compared by mixed models. RESULTS: Among 25 of 70 patients with diabetes, mean hemoglobin A(1c) during the year after leukemia diagnosis was 6.8%. Kaplan–Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). CONCLUSION: No associations were found between leukemia, diabetes, survival and glycemic control.

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