Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study

AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1...

Descripción completa

Detalles Bibliográficos
Autores principales: Wiedmeier, Julia E, Mountjoy, Luke J, Buras, Matthew R, Kosiorek, Heidi E, Coppola, Kyle E, Verona, Patricia M, Cook, Curtiss B, Karlin, Nina J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Science Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787137/
https://www.ncbi.nlm.nih.gov/pubmed/33437503
http://dx.doi.org/10.2144/fsoa-2020-0117
_version_ 1783632769139605504
author Wiedmeier, Julia E
Mountjoy, Luke J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
Karlin, Nina J
author_facet Wiedmeier, Julia E
Mountjoy, Luke J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
Karlin, Nina J
author_sort Wiedmeier, Julia E
collection PubMed
description AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan–Meier method. Hemoglobin A(1c) and glucose levels the year after leukemia diagnosis were compared by mixed models. RESULTS: Among 25 of 70 patients with diabetes, mean hemoglobin A(1c) during the year after leukemia diagnosis was 6.8%. Kaplan–Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). CONCLUSION: No associations were found between leukemia, diabetes, survival and glycemic control.
format Online
Article
Text
id pubmed-7787137
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Future Science Ltd
record_format MEDLINE/PubMed
spelling pubmed-77871372021-01-11 Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study Wiedmeier, Julia E Mountjoy, Luke J Buras, Matthew R Kosiorek, Heidi E Coppola, Kyle E Verona, Patricia M Cook, Curtiss B Karlin, Nina J Future Sci OA Research Article AIM: We examined the association between diabetes and survival in patients with acute and chronic myeloid leukemia and the association of leukemia with glycemic control. PATIENTS & METHODS: Patients with leukemia with and without diabetes (2007–2015) were retrospectively identified and matched 1:1 (n = 70 per group). Overall survival was estimated by the Kaplan–Meier method. Hemoglobin A(1c) and glucose levels the year after leukemia diagnosis were compared by mixed models. RESULTS: Among 25 of 70 patients with diabetes, mean hemoglobin A(1c) during the year after leukemia diagnosis was 6.8%. Kaplan–Meier-estimated 3-year survival was 46% for diabetes patients versus 45% for controls (p = 0.79). CONCLUSION: No associations were found between leukemia, diabetes, survival and glycemic control. Future Science Ltd 2020-10-26 /pmc/articles/PMC7787137/ /pubmed/33437503 http://dx.doi.org/10.2144/fsoa-2020-0117 Text en © 2020 Mayo Foundation for Medical Education and Research This work is licensed under the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Wiedmeier, Julia E
Mountjoy, Luke J
Buras, Matthew R
Kosiorek, Heidi E
Coppola, Kyle E
Verona, Patricia M
Cook, Curtiss B
Karlin, Nina J
Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title_full Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title_fullStr Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title_full_unstemmed Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title_short Mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
title_sort mortality and glycemic control among patients with acute and chronic myeloid leukemia and diabetes: a case–control study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787137/
https://www.ncbi.nlm.nih.gov/pubmed/33437503
http://dx.doi.org/10.2144/fsoa-2020-0117
work_keys_str_mv AT wiedmeierjuliae mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT mountjoylukej mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT burasmatthewr mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT kosiorekheidie mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT coppolakylee mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT veronapatriciam mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT cookcurtissb mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy
AT karlinninaj mortalityandglycemiccontrolamongpatientswithacuteandchronicmyeloidleukemiaanddiabetesacasecontrolstudy

Ejemplares similares