Development of an orally-administrable tumor vasculature-targeting therapeutic using annexin A1-binding D-peptides

We previously reported that IF7 peptide, which binds to the annexin A1 (ANXA1) N-terminus, functions as a tumor vasculature-targeted drug delivery vehicle after intravenous injection. To enhance IF7 stability in vivo, we undertook mirror-image peptide phage display using a synthetic D-peptide repres...

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Detalles Bibliográficos
Autores principales: Nonaka, Motohiro, Mabashi-Asazuma, Hideaki, Jarvis, Donald L., Yamasaki, Kazuhiko, Akama, Tomoya O., Nagaoka, Masato, Sasai, Toshio, Kimura-Takagi, Itsuko, Suwa, Yoichi, Yaegashi, Takashi, Huang, Chun-Teng, Nishizawa-Harada, Chizuko, Fukuda, Michiko N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787448/
https://www.ncbi.nlm.nih.gov/pubmed/33406123
http://dx.doi.org/10.1371/journal.pone.0241157

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