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Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada

OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impa...

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Detalles Bibliográficos
Autores principales: Shafer, Leigh Anne, Nesca, Marcello, Balshaw, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787456/
https://www.ncbi.nlm.nih.gov/pubmed/33406102
http://dx.doi.org/10.1371/journal.pone.0244537
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author Shafer, Leigh Anne
Nesca, Marcello
Balshaw, Robert
author_facet Shafer, Leigh Anne
Nesca, Marcello
Balshaw, Robert
author_sort Shafer, Leigh Anne
collection PubMed
description OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impact that social distancing relaxation may have on the pandemic. METHODS: We fit a mathematical model to empirically estimated numbers of people infected, recovered, and died from COVID-19 in Manitoba. We then explored the impact of social distancing relaxation on: (a) time until near elimination of COVID-19 (< one case per million), (b) time until peak prevalence, (c) proportion of the population infected within one year, (d) peak prevalence, and (e) deaths within one year. RESULTS: Assuming a closed population, near elimination of COVID-19 in Manitoba could have been achieved in 4–6 months (by July or August) if there were no relaxation of social distancing. Relaxing to 15% of pre-COVID effective contacts may extend the local epidemic for more than two years (median 2.1). Relaxation to 50% of pre-COVID effective contacts may result in a peak prevalence of 31–38% of the population, within 3–4 months of initial relaxation. CONCLUSION: Slight relaxation of social distancing may immensely impact the pandemic duration and expected peak prevalence. Only holding the course with respect to social distancing may have resulted in near elimination before Fall of 2020; relaxing social distancing to 15% of pre-COVID-19 contacts will flatten the epidemic curve but greatly extend the duration of the pandemic.
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spelling pubmed-77874562021-01-14 Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada Shafer, Leigh Anne Nesca, Marcello Balshaw, Robert PLoS One Research Article OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impact that social distancing relaxation may have on the pandemic. METHODS: We fit a mathematical model to empirically estimated numbers of people infected, recovered, and died from COVID-19 in Manitoba. We then explored the impact of social distancing relaxation on: (a) time until near elimination of COVID-19 (< one case per million), (b) time until peak prevalence, (c) proportion of the population infected within one year, (d) peak prevalence, and (e) deaths within one year. RESULTS: Assuming a closed population, near elimination of COVID-19 in Manitoba could have been achieved in 4–6 months (by July or August) if there were no relaxation of social distancing. Relaxing to 15% of pre-COVID effective contacts may extend the local epidemic for more than two years (median 2.1). Relaxation to 50% of pre-COVID effective contacts may result in a peak prevalence of 31–38% of the population, within 3–4 months of initial relaxation. CONCLUSION: Slight relaxation of social distancing may immensely impact the pandemic duration and expected peak prevalence. Only holding the course with respect to social distancing may have resulted in near elimination before Fall of 2020; relaxing social distancing to 15% of pre-COVID-19 contacts will flatten the epidemic curve but greatly extend the duration of the pandemic. Public Library of Science 2021-01-06 /pmc/articles/PMC7787456/ /pubmed/33406102 http://dx.doi.org/10.1371/journal.pone.0244537 Text en © 2021 Shafer et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Shafer, Leigh Anne
Nesca, Marcello
Balshaw, Robert
Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title_full Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title_fullStr Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title_full_unstemmed Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title_short Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
title_sort relaxation of social distancing restrictions: model estimated impact on covid-19 epidemic in manitoba, canada
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787456/
https://www.ncbi.nlm.nih.gov/pubmed/33406102
http://dx.doi.org/10.1371/journal.pone.0244537
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