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Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada
OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impa...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787456/ https://www.ncbi.nlm.nih.gov/pubmed/33406102 http://dx.doi.org/10.1371/journal.pone.0244537 |
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author | Shafer, Leigh Anne Nesca, Marcello Balshaw, Robert |
author_facet | Shafer, Leigh Anne Nesca, Marcello Balshaw, Robert |
author_sort | Shafer, Leigh Anne |
collection | PubMed |
description | OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impact that social distancing relaxation may have on the pandemic. METHODS: We fit a mathematical model to empirically estimated numbers of people infected, recovered, and died from COVID-19 in Manitoba. We then explored the impact of social distancing relaxation on: (a) time until near elimination of COVID-19 (< one case per million), (b) time until peak prevalence, (c) proportion of the population infected within one year, (d) peak prevalence, and (e) deaths within one year. RESULTS: Assuming a closed population, near elimination of COVID-19 in Manitoba could have been achieved in 4–6 months (by July or August) if there were no relaxation of social distancing. Relaxing to 15% of pre-COVID effective contacts may extend the local epidemic for more than two years (median 2.1). Relaxation to 50% of pre-COVID effective contacts may result in a peak prevalence of 31–38% of the population, within 3–4 months of initial relaxation. CONCLUSION: Slight relaxation of social distancing may immensely impact the pandemic duration and expected peak prevalence. Only holding the course with respect to social distancing may have resulted in near elimination before Fall of 2020; relaxing social distancing to 15% of pre-COVID-19 contacts will flatten the epidemic curve but greatly extend the duration of the pandemic. |
format | Online Article Text |
id | pubmed-7787456 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-77874562021-01-14 Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada Shafer, Leigh Anne Nesca, Marcello Balshaw, Robert PLoS One Research Article OBJECTIVES: The unprecedented worldwide social distancing response to COVID-19 resulted in a quick reversal of escalating case numbers. Recently, local governments globally have begun to relax social distancing regulations. Using the situation in Manitoba, Canada as an example, we estimated the impact that social distancing relaxation may have on the pandemic. METHODS: We fit a mathematical model to empirically estimated numbers of people infected, recovered, and died from COVID-19 in Manitoba. We then explored the impact of social distancing relaxation on: (a) time until near elimination of COVID-19 (< one case per million), (b) time until peak prevalence, (c) proportion of the population infected within one year, (d) peak prevalence, and (e) deaths within one year. RESULTS: Assuming a closed population, near elimination of COVID-19 in Manitoba could have been achieved in 4–6 months (by July or August) if there were no relaxation of social distancing. Relaxing to 15% of pre-COVID effective contacts may extend the local epidemic for more than two years (median 2.1). Relaxation to 50% of pre-COVID effective contacts may result in a peak prevalence of 31–38% of the population, within 3–4 months of initial relaxation. CONCLUSION: Slight relaxation of social distancing may immensely impact the pandemic duration and expected peak prevalence. Only holding the course with respect to social distancing may have resulted in near elimination before Fall of 2020; relaxing social distancing to 15% of pre-COVID-19 contacts will flatten the epidemic curve but greatly extend the duration of the pandemic. Public Library of Science 2021-01-06 /pmc/articles/PMC7787456/ /pubmed/33406102 http://dx.doi.org/10.1371/journal.pone.0244537 Text en © 2021 Shafer et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Shafer, Leigh Anne Nesca, Marcello Balshaw, Robert Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title | Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title_full | Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title_fullStr | Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title_full_unstemmed | Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title_short | Relaxation of social distancing restrictions: Model estimated impact on COVID-19 epidemic in Manitoba, Canada |
title_sort | relaxation of social distancing restrictions: model estimated impact on covid-19 epidemic in manitoba, canada |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787456/ https://www.ncbi.nlm.nih.gov/pubmed/33406102 http://dx.doi.org/10.1371/journal.pone.0244537 |
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