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BUB-1 targets PP2A:B56 to regulate chromosome congression during meiosis I in C. elegans oocytes
Protein Phosphatase 2A (PP2A) is a heterotrimer composed of scaffolding (A), catalytic (C), and regulatory (B) subunits. PP2A complexes with B56 subunits are targeted by Shugoshin and BUBR1 to protect centromeric cohesion and stabilise kinetochore–microtubule attachments in yeast and mouse meiosis....
Autores principales: | Bel Borja, Laura, Soubigou, Flavie, Taylor, Samuel J P, Fraguas Bringas, Conchita, Budrewicz, Jacqueline, Lara-Gonzalez, Pablo, Sorensen Turpin, Christopher G, Bembenek, Joshua N, Cheerambathur, Dhanya K, Pelisch, Federico |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7787666/ https://www.ncbi.nlm.nih.gov/pubmed/33355089 http://dx.doi.org/10.7554/eLife.65307 |
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